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RNA and DNA Diagnostics

  • Volker A. Erdmann
  • Stefan Jurga
  • Jan Barciszewski

Part of the RNA Technologies book series (RNATECHN)

Table of contents

  1. Front Matter
    Pages i-x
  2. Diego Voccia, Ilaria Palchetti
    Pages 1-19
  3. Christopher Pöhlmann, Mathias Sprinzl
    Pages 21-45
  4. Benoît Piro, Vincent Noël, Steeve Reisberg
    Pages 47-80
  5. Vincent Noel, Benoit Piro, Steeve Reisberg
    Pages 81-106
  6. Darija Muharemagic, Maxim V. Berezovski
    Pages 107-121
  7. Tian Ye, Ran Tong, Zhiqiang Gao
    Pages 123-144
  8. Allen W. Nicholson, Shiv K. Redhu, Alex Stopar, Lucia Coral, Vincenzo Carnevale, Matteo Castronovo
    Pages 183-204
  9. Anna Weis, Fang Liang, Jing Gao, Ross T. Barnard, Simon Corrie
    Pages 205-224
  10. Prakash Shrestha, Shankar Mandal, Hanbin Mao
    Pages 241-258
  11. Karin Lemuth, Steffen Rupp
    Pages 259-280
  12. D. Cibran Perez-Gonzalez, J. Carlos Penedo
    Pages 297-332
  13. Adam Mitchell, Amanda Marie James, Tamas Alexy, Gang Bao, Charles D. Searles
    Pages 333-349

About this book

Introduction

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”

Keywords

DNA and RNA targeted analyses aptamers gene regulation nucleic acid-based diagnostics nucleic acids technologies

Editors and affiliations

  • Volker A. Erdmann
    • 1
  • Stefan Jurga
    • 2
  • Jan Barciszewski
    • 3
  1. 1.Free University of Berlin Institute of Chemistry/BiochemistryThielallee 63Germany
  2. 2.Nanobiomedical CenterAdam Mickiewicz UniversityUmultowska 85 PoznańPoland
  3. 3.Institute of Bioorganic Chemistry of the Polish Academy of SciencesZ. Noskowskiego 12/14 PoznańPoland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-17305-4
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-17304-7
  • Online ISBN 978-3-319-17305-4
  • Series Print ISSN 2197-9731
  • Series Online ISSN 2197-9758
  • Buy this book on publisher's site
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