© 2015

Breast Cancer, Fertility Preservation and Reproduction

  • Nicoletta Biglia
  • Fedro Alessandro Peccatori


  • Describes all the available options for fertility preservation in breast cancer patients

  • Explains the impact of breast cancer treatment on fertility

  • Covers family planning in breast cancer patients/survivors and women at high risk of breast and ovarian cancer

  • Offers guidance on when it is safe to become pregnant after breast cancer


Table of contents

  1. Front Matter
    Pages i-vii
  2. Fabio Parazzini, Antonella Villa, Giampiero Polverino, Stefania Noli, Giovanna Scarfone
    Pages 1-9
  3. Joyce G. Habib, Hatem A. Azim Jr.
    Pages 11-27
  4. Lorenzo Rossi, Olivia Pagani
    Pages 29-43
  5. Alberto Revelli, Francesca Salvagno, Simona Casano, Luisa Delle Piane, Chiara Benedetto
    Pages 45-59
  6. Giovanni Codacci-Pisanelli, Giovanna Scarfone, Lino Del Pup, Eleonora Zaccarelli, Fedro A. Peccatori
    Pages 61-70
  7. Nicoletta Biglia, Nicoletta Tomasi Cont, Valentina Bounous, Marta d’Alonzo, Silvia Pecchio
    Pages 71-82
  8. Shani Paluch-Shimon, Dror Meirow, Jordana Hyman
    Pages 83-102

About this book


This book provides a comprehensive overview on fertility issues in patients with breast cancer .

The impact of  treatments on fertility is clearly  explained and all the available options for fertility

preservation are discussed. Guidance is offered on management options when breast cancer arises

during pregnancy and when pregnancy occurs after breast cancer. In addition, the management of

high risk patients with regard to their reproductive life, risks of assisted reproduction, optimal contraception is enclosed. Answers are provided to a wide range of questions, including:

What fertility sparing options are available for ER+ patients? Is ovarian tissue freezing ready for prime time? What is the role of LHRH analogues ?What is the impact of pregnancy after breast cancer ? What advice should be given on the timing of pregnancy after treatment? Is breast feeding possible? Physicians will find this book an invaluable aid in providing flawless counseling to their patients and ensuring that they receive optimal management.


Assisted reproduction in breast cancer patients Breast cancer during pregnancy Breastfeeding Chemotherapy Contraception Endocrine therapy Fertility preservation in breast cancer patients Pregnancy after breast cancer

Editors and affiliations

  • Nicoletta Biglia
    • 1
  • Fedro Alessandro Peccatori
    • 2
  1. 1.Department of Obstetrics and GynaecologyUniversity of Torino School of Medicine, Mauriziano Umberto I HospitalTorinoItaly
  2. 2.Fertility and Procreation UnitIstituto Europeo di OncologiaMilanoItaly

About the editors

Nicoletta Biglia MD, PhD,  is Associate Professor of  Gynaecology  and Obstetrics at the University of Torino Medical School and Deputy Director of the Academic Division of Obstetrics and Gynecology and Breast diseases at the Mauriziano Umberto I Hospital in Torino. Dr Biglia graduated in Medicine and Surgery at the University of Turin in 1986 summa cum laude, she specialized in Obstetrics and Gynaecology  in 1990,  got the PhD in Gynecological Oncology in 1995 and the European Certificate in Laparoscopic Pelvic Surgery in the year 2000. Hers clinical activity has been primarily devoted to the diagnosis and surgical treatment of breast and pelvic tumors. She has a more than 20 years long experience in radical pelvic surgery, in oncoplastic breast cancer surgery, and has refined hers skills through several residencies and visits in Reference Institutions in Europe and USA. She has developed a special research interest in the relationship between hormones, oncogenes and breast cancer risk, in the procedures and drugs aimed at reducing the impact of cancer and cancer related treatments on the quality of life of cancer survivors, and in innovative surgical techniques both in pelvic and breast oncology. Dr Biglia has promoted and partecipated in several international clinical trials in the fields of Gynecological Oncology, Menopause and Breast Cancer. She is member of National and International Scientific Societies: European Society of Gynaecological Oncology (ESGO), International Gynaecologic Cancer Society (IGCS), European Society of Mastology (EUSOMA), Italian Society of Gynaecological Oncologi (SIOG), Italian Breast Network (Senonetwork).  She has served in the Board of the Italian Society of Menopause (SIM) for two terms and from 2005 to 2014 in the Board of  the Italian Society of Gynaecological Oncology (SIOG). She has authored more than 120 papers in international journals and has participated as an invited speaker in national and international conferences, congresses, and courses.

Fedro Alessandro Peccatori. Since 1994 he has been working at the European Institute of Oncology, IRCCS, Milan, in the Division of Haemato-Oncology, Medical Oncology and Gynecology. In 2011, he was appointed Director of the Fertility and Procreation Unit, which is now integrated within the Gynecologic Oncology Program. Dr. Peccatori’s main research interests are fertility preservation and counseling in young oncological patients, pharmacological protection of ovarian function during chemotherapy, clinical and molecular characterization of pregnancy-associated cancers, and research protocols for the treatment of breast and gynecological malignancies. He has been a speaker at a number of international meetings, and in the past 5 years has taught at the Universities of Varese, Pavia, and Milan. He is Deputy Scientific Director at the European School of Oncology, with responsibility for educational activities. As President of PROFERT (Society for the Preservation of Fertility) he has contributed in building up the Italian network for fertility preservation in cancer patients. He has acted as referee for various leading journals and is on the editorial committee of ecancermedicalscience and Cancerworld. Dr. Peccatori is the lead or co-author of 125 publications in peer-reviewed journals indexed in PubMed and is co-editor of the Springer book Cancer and Pregnancy (2008).

Bibliographic information

  • Book Title Breast Cancer, Fertility Preservation and Reproduction
  • Editors Nicoletta Biglia
    Fedro Alessandro Peccatori
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-17277-4
  • Softcover ISBN 978-3-319-36059-1
  • eBook ISBN 978-3-319-17278-1
  • Edition Number 1
  • Number of Pages VII, 102
  • Number of Illustrations 0 b/w illustrations, 1 illustrations in colour
  • Topics Reproductive Medicine
  • Buy this book on publisher's site
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