© 2015

Tryptophan Metabolism: Implications for Biological Processes, Health and Disease

  • Atilla Engin
  • Ayse Basak Engin

Part of the Molecular and Integrative Toxicology book series (MOLECUL)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Atilla Engin, Ayse Basak Engin
    Pages 31-54
  3. Kathrin Becker, Giorgio Ciprandi, Johanna Gostner, Heinz Kofler, Dietmar Fuchs
    Pages 55-73
  4. Evren Doruk Engin
    Pages 75-94
  5. Ugur Unluturk, Tomris Erbas
    Pages 147-171
  6. Daniel P. Cardinali, Daniel E. Vigo, Natividad Olivar, María F. Vidal, Luis I. Brusco
    Pages 197-238
  7. Oguz Kokturk, Asiye Kanbay
    Pages 239-252
  8. Ibrahim C. Haznedaroglu
    Pages 253-267
  9. Atilla Engin, Ayse Basak Engin
    Pages 269-289
  10. S. Altug Kesikli, Nilufer Guler
    Pages 291-333
  11. Atilla Engin
    Pages 361-377
  12. Back Matter
    Pages 379-382

About this book


This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacterial tryptophan biosynthesis and novel antimicrobials.

Tryptophan Metabolism: Implications for Biological Processes, Health and Disease presents fundamental information on tryptophan related metabolic pathways and metabolites, implications of these products for specific biological processes, diseases and conditions.

This book focuses on effects of tryptophan metabolites on human health and will appeal to researchers, clinicians and students within this field.


Immunotoxicity Melatonin Metabolic Oxidative stress Seratonin Tryptophan

Editors and affiliations

  • Atilla Engin
    • 1
  • Ayse Basak Engin
    • 2
  1. 1.Faculty of Medicine, Department of General SurgeryGazi UniversityBesevler, AnkaraTurkey
  2. 2.Faculty of Pharmacy, Department of ToxicologyGazi UniversityHipodrom, AnkaraTurkey

Bibliographic information

Industry Sectors
Health & Hospitals
Pharmacology & Toxicology
Consumer Packaged Goods


“This is a biochemical physiology textbook concerning the metabolic pathways of serotonin, kyneurenic, melatonin, and related chemicals in brain/mind disorders. … I recommend this book to all students and practitioners in Neurology, Neurophysiology, and Psychiatry.” (Joseph J. Grenier,, May, 2015)