Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

  • Jamie C. DeWitt

Part of the Molecular and Integrative Toxicology book series (MOLECUL)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Christopher Lau
    Pages 1-21
  3. Kayoko Kato, Xiaoyun Ye, Antonia M. Calafat
    Pages 51-76
  4. Jessica L. Reiner, Benjamin J. Place
    Pages 127-150
  5. Naomi Kudo
    Pages 151-175
  6. Qixiao Jiang, Hui Gao, Lei Zhang
    Pages 177-201
  7. Barbara D. Abbott
    Pages 203-218
  8. Henrik Viberg, Espen Mariussen
    Pages 219-238
  9. Deborah E. Keil
    Pages 239-248
  10. Casey E. Reed, Suzanne E. Fenton
    Pages 249-264
  11. Gerald L. Kennedy, J. Morel Symons
    Pages 265-304
  12. Naila Khalil, Miryoung Lee, Kyle Steenland
    Pages 305-335
  13. John Wambaugh
    Pages 337-361
  14. John L. Butenhoff, Joseph V. Rodricks
    Pages 363-418
  15. Jamie C. DeWitt
    Pages 479-482
  16. Back Matter
    Pages 483-495

About this book


This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage, and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight.

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provides critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health.

This book will be a useful resource for toxicologists, environmental chemists, risk assessors, and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.


developmental toxicity dosimetric anchoring endocrine toxicity perfluorinated compounds toxicity

Editors and affiliations

  • Jamie C. DeWitt
    • 1
  1. 1.Brody School of MedicineEast Carolina UniversityGreenvilleUSA

Bibliographic information

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