© 2015

Advanced Time-Correlated Single Photon Counting Applications

  • Wolfgang Becker
  • Edited by the originator of the technique

  • Written by expert users of the technique

  • Provides clear connection of instrumental principles, physical effects used, and applications in life sciences

  • Stresses applications in medicine and biology

  • Helps users from non-physics and non-engineering areas to understand the technique and optimize their experiment


Part of the Springer Series in Chemical Physics book series (CHEMICAL, volume 111)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Wolfgang Becker
    Pages 1-63
  3. Wolfgang Becker, Vladislav Shcheslavskiy, Hauke Studier
    Pages 65-117
  4. Klaus Suhling, Liisa M. Hirvonen, James A. Levitt, Pei-Hua Chung, Carolyn Tregido, Alix le Marois et al.
    Pages 119-188
  5. Thomas Gensch, Verena Untiet, Arne Franzen, Peter Kovermann, Christoph Fahlke
    Pages 189-211
  6. James Jenkins, Ruslan I. Dmitriev, Dmitri B. Papkovsky
    Pages 225-247
  7. Ammasi Periasamy, Nirmal Mazumder, Yuansheng Sun, Kathryn G. Christopher, Richard N. Day
    Pages 249-276
  8. Ludovic Richert, Pascal Didier, Hugues de Rocquigny, Yves Mély
    Pages 277-307
  9. Dhanushka Wickramasinghe, Randi Timerman, Jillian Bartusek, Ahmed A. Heikal
    Pages 339-355
  10. Sagar V. Kathuria, Osman Bilsel
    Pages 357-384
  11. Steven S. Vogel, Tuan A. Nguyen, Paul S. Blank, B. Wieb van der Meer
    Pages 385-406
  12. Alzbeta Marcek Chorvatova
    Pages 407-434
  13. Alex J. Walsh, Amy T. Shah, Joe T. Sharick, Melissa C. Skala
    Pages 435-456
  14. Washington Y. Sanchez, Michael Pastore, Isha N. Haridass, Karsten König, Wolfgang Becker, Michael S. Roberts
    Pages 457-508
  15. Dietrich Schweitzer, Martin Hammer
    Pages 509-540
  16. Adam Liebert, Michal Kacprzak, Daniel Milej, Wolfgang Becker, Anna Gerega, Piotr Sawosz et al.
    Pages 541-559
  17. Heidrun Wabnitz, Mikhail Mazurenka, Laura Di Sieno, Gianluca Boso, Wolfgang Becker, Katja Fuchs et al.
    Pages 561-585
  18. Giovanna Quarto, Alessandro Torricelli, Lorenzo Spinelli, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni
    Pages 587-611

About this book


This book is an attempt to bridge the gap between the instrumental principles of multi-dimensional time-correlated single photon counting (TCSPC) and typical applications of the technique. Written by an originator of the technique and by sucessful users, it covers the basic principles of the technique, its interaction with optical imaging methods and its application to a wide range of experimental tasks in life sciences and clinical research.

The book is recommended for all users of time-resolved detection techniques in biology, bio-chemistry, spectroscopy of live systems, live cell microscopy, clinical imaging, spectroscopy of single molecules, and other applications that require the detection of low-level light signals at single-photon sensitivity and picosecond time resolution.


Application of TCSPC in Biology Clinical and Preclinical Application of TCSPC Single Photon Counting Single Photon Spectroscopy TCSPC Applications TCSPC Review TCSPC Techniques Time-correlated Optical Technique

Editors and affiliations

  • Wolfgang Becker
    • 1
  1. 1.Becker & Hickl GmbHBerlinGermany

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