© 2015

The Networking of Chaperones by Co-chaperones

Control of Cellular Protein Homeostasis

  • Gregory Lloyd Blatch
  • Adrienne Lesley Edkins


  • This is the only book that specifically reviews the knowledge on co-chaperones as opposed to chaperones

  • Excellent information resource for researchers entering the specialized field of cell stress and chaperones

  • Excellent information resource for researchers in the broader field of diseases related to protein folding (e.g. Alzheimers)


Part of the Subcellular Biochemistry book series (SCBI, volume 78)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Naihsuan C. Guy, Yenni A. Garcia, Jeffrey C. Sivils, Mario D. Galigniana, Marc B. Cox
    Pages 35-68
  3. Swati Baindur-Hudson, Adrienne L. Edkins, Gregory L. Blatch
    Pages 69-90
  4. Douglas M. Cyr, Carlos H. Ramos
    Pages 91-102
  5. Stuart K. Calderwood
    Pages 103-112
  6. Alexandra Beatrice Rehn, Johannes Buchner
    Pages 113-131
  7. Weiming Ni, Odutayo O. Odunuga
    Pages 133-152
  8. Aileen Boshoff
    Pages 153-178
  9. Armin Melnyk, Heiko Rieger, Richard Zimmermann
    Pages 179-200
  10. Neta Regev-Rudzki, Kip Gabriel, Dejan Bursać
    Pages 201-217
  11. Emma J. Duncan, Michael E. Cheetham, J. Paul Chapple, Jacqueline van der Spuy
    Pages 243-273
  12. Back Matter
    Pages 275-276

About this book


Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.


Cell Stress Cellular Networks Chaperones Co-chaperones Heat Shock Proteins Protein Folding

Editors and affiliations

  • Gregory Lloyd Blatch
    • 1
  • Adrienne Lesley Edkins
    • 2
  1. 1.Victoria University, College of Health and BiomedicineMelbourneAustralia
  2. 2.Department of Biochemistry and MicrobiologyRhodes University, Biomedical Biotechnology Research UnitGrahamstownSouth Africa

Bibliographic information

  • Book Title The Networking of Chaperones by Co-chaperones
  • Book Subtitle Control of Cellular Protein Homeostasis
  • Editors Gregory Lloyd Blatch
    Adrienne Lesley Edkins
  • Series Title Subcellular Biochemistry
  • Series Abbreviated Title Subcellular Biochemistry
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-11730-0
  • Softcover ISBN 978-3-319-38149-7
  • eBook ISBN 978-3-319-11731-7
  • Series ISSN 0306-0225
  • Edition Number 1
  • Number of Pages XV, 276
  • Number of Illustrations 4 b/w illustrations, 31 illustrations in colour
  • Topics Biomedicine, general
    Life Sciences, general
    Biochemistry, general
  • Buy this book on publisher's site
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