© 2015

Antiphospholipid Antibody Syndrome

From Bench to Bedside

  • Pier Luigi Meroni


  • Provides up-to-date knowledge on the pathogenesis and management of the syndrome

  • Presents and discusses innovative treatments in addition to standard treatment options

  • Describes the involvement of other organs or organ systems


Part of the Rare Diseases of the Immune System book series (RDIS)

Table of contents

  1. Front Matter
    Pages i-x
  2. Alessandra Soriano, Miri Blank, Yehuda Shoenfeld
    Pages 1-12
  3. Alessandra Banzato, Vittorio Pengo
    Pages 13-23
  4. Pier Luigi Meroni, Chiara Crotti, Cecilia Chighizola
    Pages 25-35
  5. Ronald H. W. M. Derksen, Ruth Fritsch-Stork
    Pages 47-59
  6. Maria Gerosa, Francesca Rovelli
    Pages 61-74
  7. Micaela Fredi, Angela Tincani
    Pages 75-87
  8. Cecilia Beatrice Chighizola, Davide Sangalli, Barbara Corrà, Vincenzo Silani, Laura Adobbati
    Pages 89-102
  9. Nicoletta Mezzina, Renato Alberto Sinico
    Pages 103-112
  10. Wilma Barcellini, Carolina Artusi
    Pages 113-126
  11. Gentian Denas, Vittorio Pengo
    Pages 127-150
  12. Angelo Valerio Marzano, Silvia Alberti Violetti, Riccardo Lazzari, Emilio Berti
    Pages 151-161
  13. Domenico Prisco, Giacomo Emmi, Elena Silvestri, Lucia Ciucciarelli, Elena Niccolai, Mario Milco D’Elios et al.
    Pages 169-184
  14. Simon Braham, Paolo Bucciarelli, Marco Moia
    Pages 185-192
  15. Barbara Acaia, Federica Rossi, Cecilia Beatrice Chighizola
    Pages 193-206
  16. Francesca Dall’Ara, Cecilia Nalli, Laura Andreoli
    Pages 207-218
  17. Cecilia Beatrice Chighizola, Tania Ubiali
    Pages 219-232
  18. Anisur Rahman, Maria Gabriella Raimondo
    Pages 233-248

About this book


This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss or complications are explained. The main clinical manifestations and classification criteria are described and diagnostic tools, identified. Close attention is paid to the nature of the involvement of other organs or organ systems in APS, including the nervous, endocrine, hematologic, cardiovascular, and gastrointestinal systems, the kidney, the skin, and the eye. Specific chapters describe the treatment of the different symptoms, the preventive therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome


Antiphospholipid antibody syndrome Autoantibodies Hughes syndrome Phospholipid binding proteins Pregnancy complications Thrombosis

Editors and affiliations

  • Pier Luigi Meroni
    • 1
  1. 1.Department of RheumatologyGaetano Pini InstituteMilanItaly

Bibliographic information

  • Book Title Antiphospholipid Antibody Syndrome
  • Book Subtitle From Bench to Bedside
  • Editors Pier Luigi Meroni
  • Series Title Rare Diseases of the Immune System
  • Series Abbreviated Title Rare Diseases of Immune System
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-11043-1
  • Softcover ISBN 978-3-319-35710-2
  • eBook ISBN 978-3-319-11044-8
  • Series ISSN 2282-6505
  • Series E-ISSN 2283-6403
  • Edition Number 1
  • Number of Pages X, 267
  • Number of Illustrations 4 b/w illustrations, 15 illustrations in colour
  • Topics Hematology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology


From the book reviews:

“The purpose is to provide an overview of this very difficult subject that will benefit bench researchers as well as bedside clinicians. The book would serve any audience who wants to know more about antiphospholipid syndrome. … This is an excellent, up-to-date overview of antiphospholipid syndrome. It will serve as a handy tool to get more information on the topic.” (Dany V. Thekkemuriyil, Doody’s Book Reviews, February, 2015)