An Overview

  • Gert Folkerts
  • Johan Garssen

Part of the AAPS Advances in the Pharmaceutical Sciences Series book series (AAPS, volume 12)

Table of contents

  1. Front Matter
    Pages i-xv
  2. General

    1. Front Matter
      Pages 1-1
    2. Seil Sagar, Gert Folkerts, Johan Garssen
      Pages 3-8
    3. Geert Houben, Marty Blom, Jolanda van Bilsen, Lisette Krul
      Pages 9-27
    4. Tamar C. Weenen, Kenneth Fernald, Esther S. Pronker, Harry Commandeur, Eric Claassen
      Pages 29-52
  3. Inflammation and Immunity

    1. Front Matter
      Pages 53-53
    2. Julia König, Robert-Jan Brummer
      Pages 55-73
    3. Kevan Jacobson, Philip C. Calder
      Pages 75-89
    4. Sophie Layé, Charlotte Madore, Jean-Christophe Delpech, Corinne Joffre, Agnès Nadjar
      Pages 91-112
    5. Shizuo Yamada, Shingen Misaka, Yoshihiko Ito, Hiroshi Watanabe, Keizo Umegaki
      Pages 189-211
    6. Heather E. Rasmussen, Bryana R. Piazza, Christopher B. Forsyth, Ali Keshavarzian
      Pages 213-242
    7. Matheus Correa-Costa, Leo E. Otterbein
      Pages 243-256
  4. Cancer and Cachexia

    1. Front Matter
      Pages 257-257
    2. Josep M. Argilés, Francisco Javier López-Soriano, Britta Stemmler, Sílvia Busquets
      Pages 259-273
    3. Alessandro Laviano, Chiara Gori, Martina Stronati, Alessia Mari, Serena Rianda
      Pages 295-304
  5. Allergy

    1. Front Matter
      Pages 343-343
    2. Alma J. Nauta, Hugo van Bever
      Pages 345-357
    3. Prescilla V. Jeurink, Laura A. P. D. Meulenbroek, Johan Garssen, Léon M. J. Knippels
      Pages 373-391
  6. Brain and Neuroimmunity

  7. Back Matter
    Pages 481-484

About this book


This volume examines the effects of natural products and functional/medical foods (nutritional programming) on disease management. It specifically focuses on diseases related to inflammation and immunity, cancer and cachexia, allergies, and brain and neuro/immune. As both pharmacologists and nutritionists are recognizing that the one disease/one target/one drug (or nutrient) concept will be less successful than in the past, this book aims to stress the importance of a multi-target approach versus a single-target approach. It also presents aspects of molecular characteristics of food ingredients toward clinical effectiveness and relevance.


The interest in food in health and disease has exploded in the past few years, and publications on the microbiome can be found in all major scientific journals and newspapers. A new concept uses functional foods hand in hand with standard pharmacological therapies, which can be conceptualized in the term “pharma-nutrition.” With the complementary values of pharma and nutrition, scientists might be able to overcome the increased incidence worldwide of complex multi-factorial disorders, chronic and degenerative diseases in particular.


allergy fatty acids functional foods inflammation nutraceuticals

Editors and affiliations

  • Gert Folkerts
    • 1
  • Johan Garssen
    • 2
  1. 1.PharmacologyUtrecht UniversityThe Netherlands
  2. 2.ImmunopharmacologyUtrecht UniversityThe Netherlands

Bibliographic information

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