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Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry

  • Rainer Cramer

Table of contents

  1. Front Matter
    Pages i-xi
  2. Fundamental Improvements in MALDI

    1. Front Matter
      Pages 1-1
    2. U. Bahr, T. W. Jaskolla
      Pages 3-35
    3. Pavel Ryumin, Rainer Cramer
      Pages 37-47
  3. Applications of Liquid MALDI Mass Spectrometry

    1. Front Matter
      Pages 49-49
    2. Kanjana Wiangnon, Rainer Cramer
      Pages 65-76
    3. Joanna Tucher, Prasath Somasundaram, Andreas Tholey
      Pages 77-90
  4. Advances in MALDI Mass Spectrometry Imaging

    1. Front Matter
      Pages 91-91
    2. Aurélien Thomas, Nathan Heath Patterson, Martin Dufresne, Pierre Chaurand
      Pages 129-147
    3. Bindesh Shrestha, Callee M. Walsh, Gregory R. Boyce, Peter Nemes
      Pages 149-167
    4. Milad Nazari, David C. Muddiman
      Pages 169-182
  5. MS Profiling of Clinical Samples

    1. Front Matter
      Pages 183-183
    2. Stephane Camuzeaux, John F. Timms
      Pages 185-196
    3. Arthur B. Pranada, Gerold Schwarz, Markus Kostrzewa
      Pages 197-225
    4. Markus Kostrzewa, Arthur B. Pranada
      Pages 227-246
  6. MALDI Biotyping Beyond the Clinic

    1. Front Matter
      Pages 247-247
    2. Bogdan Munteanu, Carsten Hopf
      Pages 249-262
    3. Rosa Anna Siciliano, Diego d’Esposito, Maria Fiorella Mazzeo
      Pages 263-277
  7. Back Matter
    Pages 279-286

About this book

Introduction

This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on  MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization).  This is an ideal book for graduate students and researchers in the field of bioanalytical sciences.

This book also:

• Showcases new techniques and applications in MALDI MS
• Demonstrates how MALDI is preferable to ESI
• Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and various application areas, such as cancer proteomics

Keywords

Bioanalysis Ionization Laser-induced desorption MALDI Mass spectrometry New analytical workflows

Editors and affiliations

  • Rainer Cramer
    • 1
  1. 1.Department of ChemistryUniversity of ReadingReadingUnited Kingdom

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