Light-Sensitive Polymeric Nanoparticles Based on Photo-Cleavable Chromophores

  • Daniel Klinger

Part of the Springer Theses book series (Springer Theses)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Daniel Klinger
    Pages 1-2
  3. Daniel Klinger
    Pages 3-4
  4. Daniel Klinger
    Pages 5-55
  5. Daniel Klinger
    Pages 57-59
  6. Daniel Klinger
    Pages 61-194
  7. Daniel Klinger
    Pages 195-199
  8. Daniel Klinger
    Pages 201-222
  9. Back Matter
    Pages 223-224

About this book

Introduction

The triggered release of functional compounds from such polymeric carriers as micelles, nanoparticles or nanogels is a rapidly developing and highly versatile concept which is expected to be one of the key approaches to future therapeutics. In his thesis, Daniel Klinger highlights the approach of stimuli-responsive microgels for such applications and discusses why especially light as a trigger has an outstanding position amongst the family of conventional stimuli. Based on these considerations, the author focuses on the design, synthesis and characterization of novel photo-sensitive microgels and nanoparticles as potential materials for the loading and light-triggered release/accessibility of functional compounds. Starting from the synthesis of photo-cleavable organic building blocks and their use in the preparation of polymeric nanoparticles, continuing to the examination of their loading and release profiles, and concluding with biological in vitro studies of the final materials, Daniel Klinger’s work is an excellent example of the multidisciplinary research needed for the successful development of new materials in this field and has led to a number of further publications in internationally respected journals.

Keywords

Hydrogel Nanoparticles Light-Sensitive Nanoparticles Light-Triggered Release Miniemulsion Polymerization Photo-Cleavable Crosslinkers Photochemical Nanotechnology Polymer Chemistry Stimuli-Responsive Microgels

Authors and affiliations

  • Daniel Klinger
    • 1
  1. 1.Materials Research InstituteUniversity of CaliforniaSanta BarbaraUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-00446-4
  • Copyright Information Springer International Publishing Switzerland 2013
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-319-00445-7
  • Online ISBN 978-3-319-00446-4
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • About this book
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