DNA Methylation

Molecular Biology and Biological Significance

  • Jean-Pierre Jost
  • Hans-Peter Saluz

Part of the EXS book series (EXS, volume 64)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Arthur Weissbach
    Pages 1-10
  3. Hanspeter Saluz, Jean-Pierre Jost
    Pages 11-26
  4. Mario Noyer-Weidner, Thomas A. Trautner
    Pages 39-108
  5. Heinrich Leonhardt, Timothy H. Bestor
    Pages 109-119
  6. R. L. P. Adams, H. Lindsay, A. Reale, C. Seivwright, S. Kass, M. Cummings et al.
    Pages 120-144
  7. Francisco Antequera, Adrian Bird
    Pages 169-185
  8. Michael Nelson, Yanping Zhang, James L. Van Etten
    Pages 186-211
  9. Eric U. Selker
    Pages 212-217
  10. E. J. Finnegan, R. I. S. Brettell, E. S. Dennis
    Pages 218-261
  11. Daniel P. Bednarik
    Pages 300-329
  12. Aharon Razin, Howard Cedar
    Pages 343-357
  13. Judith Singer-Sam, Arthur D. Riggs
    Pages 358-384
  14. Hiroyuki Sasaki, Nicholas D. Allen, M. Azim Surani
    Pages 469-486
  15. Charles H. Spruck III, William M. Rideout III, Peter A. Jones
    Pages 487-509
  16. Karin Wiebauer, Petra Neddermann, Melya Hughes, Josef Jiricny
    Pages 510-522
  17. Agnes Yeivin, Aharon Razin
    Pages 523-568
  18. Back Matter
    Pages 569-572

About this book


The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see first chapter). Recognition of its possible physiologi­ cal role in eucaryotes was first suggested in 1964 by Srinivasan and Borek (see first chapter). Since then work in a great many laboratories has established both the ubiquity of 5-methylcytosine and the catholicity of its possible regulatory function. The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of a general review. Since the publication of the 3 most recent books dealing with the subject (DNA methylation by Razin A. , Cedar H. and Riggs A. D. , 1984 Springer Verlag; Molecular Biology of DNA methylation by Adams R. L. P. and Burdon R. H. , 1985 Springer Verlag; Nucleic Acids Methylation, UCLA Symposium suppl. 128, 1989) considerable progress both in the techniques and results has been made in the field of DNA methylation. Thus we asked several authors to write chapters dealing with aspects of DNA methyla­ tion in which they are experts. This book should be most useful for students, teachers as well as researchers in the field of differentiation and gene regulation. We are most grateful to all our colleagues who were willing to spend much time and effort on the publication of this book. We also want to express our gratitude to Yan Chim Jost for her help in preparing this book.


DNA Promoter biology gene expression genes molecular biology prokaryotes

Editors and affiliations

  • Jean-Pierre Jost
    • 1
  • Hans-Peter Saluz
    • 2
  1. 1.Friedrich Miescher-InstitutBaselSwitzerland
  2. 2.IRBMPomenzia (Roma)Italy

Bibliographic information

  • DOI
  • Copyright Information Birkhäuser Basel 1993
  • Publisher Name Birkhäuser Basel
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-0348-9915-4
  • Online ISBN 978-3-0348-9118-9
  • Series Print ISSN 1023-294X
  • Buy this book on publisher's site
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