Advertisement

Medicinal Fatty Acids in Inflammation

  • Joel M. Kremer

Part of the Progress in Inflammation Research book series (PIR)

Table of contents

  1. Front Matter
    Pages i-x
  2. Vincent A. Ziboh
    Pages 45-53
  3. David F. Horrobin
    Pages 55-64
  4. David F. Horrobin
    Pages 65-71
  5. Andrea Belluzzi, Federico Miglio
    Pages 91-101
  6. Back Matter
    Pages 141-148

About this book

Introduction

This volume of Progress in Inflammation Research is a unique compilation of work performed by a wide spectrum of investigators from different medical disciplines. It is fascinating that dietary alterations of fatty acid intake can result in a range of salutory changes in a great variety of medical conditions. Most of the good scien­ tific work which has led to these observations has been performed over just the last two decades. This is of course not a very long time in the context of the history of the human species. Recently performed analysis of fat intake from paleolithic times has indicated that our hunter-gatherer ancestors consumed as much cholesterol as modern Western man, but strikingly less saturated fatty acid and more polyunsatu­ rates, including n-3 fatty acids. Wild game has the terrestrial source of n-3 incorpo­ rated in its fat since browsing animals derive 18:3n-3 (alpha-linolenic acid) natural­ ly from leafy plants. There is, however, little opportunity for modern Western man to get n-3 fatty acids from the diet if one does not consume fish. Modern agribusiness provides ani­ mal feeds high in n-6 fatty acids, mostly derived from linoleic acid (18:2n-6) in corn feed. Therefore, grazing animals have no access to alternative fatty acids in either feed or grasses, the latter containing little or none of these potentially beneficial highly polyunsaturated fatty acids.

Keywords

apoptosis autoimmune disease food food industry inflammation nervous system psoriasis rheumatism

Editors and affiliations

  • Joel M. Kremer
    • 1
  1. 1.Division of RheumatologyAlbany Medical CollegeAlbanyUSA

Bibliographic information

Industry Sectors
Pharma
Health & Hospitals
Biotechnology