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New Cytokines as Potential Drugs

  • Satwant K. Narula
  • Robert Coffman
Conference proceedings

Part of the Progress in Inflammation Research book series (PIR)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Francis M. Cuss
    Pages 1-13
  3. Satwant Narula, Sidney Smith, Paul Grint
    Pages 15-29
  4. William W. Cruikshank, Hardy Kornfeld, David M. Center
    Pages 31-51
  5. François Fossiez, Jean-François Nicolas, Serge Lebecque
    Pages 53-58
  6. Masashi Kurimoto
    Pages 59-80
  7. Hilary J. McKenna
    Pages 81-100
  8. Pablo A. Jimenez, Dale Greenwalt, Donna L. Mendrick, Mark A. Rampy, Jeffrey Su, Kam H. Leung et al.
    Pages 101-119
  9. Sergio A. Lira, Paul J. Zavodny, Daniel Lundell
    Pages 121-138
  10. Back Matter
    Pages 139-141

About these proceedings

Introduction

Over the past ten years, a number of cytokines and growth factors have proven to be as effective therapeutics. While these products have certainly established recombinant biologics as a major pharmaceutical growth sector, the continued interest in this class of drugs arises from the fact that today we have a far better understanding of the human immune response, both at a cellular and molecular level. This has resulted in a more methodical characterisation of these factors which has given clinical researchers an opportunity to plan Phase 1 clinical trials that can provide substantial information on the activity of the cytokine in humans. Currently, a great deal of effort is also being channelled into identifying cytokines from the various DNA databases. Our major objective for this book is to profile cytokines that have been recently identified. The therapeutic potential of these cytokines based on their known properties will be discussed by the authors. The main aim of this book is to provide...

Keywords

Chemokine clinical research clinical trial cytokine immune response research

Editors and affiliations

  • Satwant K. Narula
    • 1
  • Robert Coffman
    • 2
  1. 1.Schering-Plough Research InstituteKenilworthUSA
  2. 2.DNAX Research InstitutePalo AltoUSA

Bibliographic information

Industry Sectors
Pharma
Health & Hospitals
Biotechnology