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Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications

  • Maria A. Livrea

Part of the MCBU Molecular and Cell Biology Updates book series (MCBU)

Table of contents

  1. Front Matter
    Pages I-XI
  2. M. V. Gamble, W. S. Blaner
    Pages 1-16
  3. R. K. Crouch, J.-X. Ma
    Pages 59-72
  4. U. C. Dräger, E. Wagner, P. McCaffery, A. Andreadis
    Pages 73-82
  5. R. D. Semba
    Pages 97-108
  6. J. M. Creech Kraft
    Pages 109-119
  7. C. Carlberg, P. Polly
    Pages 141-149
  8. S. Kang, G. J. Fisher, J. J. Voorhees
    Pages 151-159
  9. M. I. Dawson, X. Zhang, P. D. Hobbs, L. Jong
    Pages 161-196
  10. R. Lotan, J. L. Clifford, S. M. Lippman
    Pages 221-230
  11. C. C. Geilen, B. Almond-Roesler, C. E. Orfanos
    Pages 251-259
  12. A. A. Bajoghli, B. A. Gilchrest
    Pages 261-277
  13. E. S. Klein, R. A. S. Chandraratna
    Pages 279-290
  14. Back Matter
    Pages 293-300

About this book

Introduction

Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolic pathways during oncogenesis. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on the clinical efficiency of retinoids in skin disorders and cancer. The book presents recent findings on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. It also offers a survey of the molecular and cell biochemistry of retinoids. Basic researchers in biochemistry, pharmacology and cell biology as well as clinicians will find this book very informative and up-to-date. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on clinical efficiency of retinoids in skin disorders and cancer. Basic researchers in biochemistry, pharmacology, cell biology, and clinicians will find this book very informative and up-to-date. The chapters, organized in six sections, are contributed by leading scientists who have been working in the retinoid field for decades. Their experience and competence is aknowledged worldwide.

Keywords

Activation biochemistry biology cancer cell biology genes metabolism molecular mechanisms oncogene oncogenes pharmacology regulation research signal transduction tissue

Editors and affiliations

  • Maria A. Livrea
    • 1
  1. 1.Cattedra di Chimica Biologica, Istituto di Farmacologia e FarmacognosiaUniversità di PalermoPalermoItaly

Bibliographic information

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