The Many Faces of Osteoarthritis

  • Vincent C. Hascall
  • Klaus E. Kuettner
Conference proceedings

Table of contents

  1. Front Matter
    Pages i-xl
  2. The many phases of osteoarthritis

    1. Front Matter
      Pages 1-4
    2. Audrey McAlinden, Naoshi Fukui, Linda J. Sandell
      Pages 5-16
    3. Matthew L. Warman
      Pages 17-25
    4. Ada Cole, Hans Häuselmann, Johannes Flechtenmacher, Klaus Huch, Holger Koepp, Wolfgang Eger et al.
      Pages 27-29
    5. Thorvaldur Ingvarsson
      Pages 39-44
    6. Lydia K. Wachsmuth, Beate Durchfeld-Meyer, Nadine I. Jahn, Nicole Verzijl, Uwe H. Dietz, Nicole Gerwin et al.
      Pages 45-49
    7. Back Matter
      Pages 51-60
  3. Morphogenics, development and repair

    1. Front Matter
      Pages 61-66
    2. Holger E. Koepp, Johannes Flechtenmacher, Klaus Huch, Eugene J. MA. Thonar, Gene A. Homandberg, Klaus E. Kuettner
      Pages 77-80
    3. Susan Chubinskaya, David C. Rueger, Richard A. Berger, Klaus E. Kuettner
      Pages 81-89
    4. Véronique Lefebvre, Benoit de Crombrugghe, Richard R. Behringer
      Pages 91-100
    5. Arthur Veis, Kevin Tompkins, Michel Goldberg
      Pages 101-105
    6. Back Matter
      Pages 107-112
  4. Matrix molecules in cartilage and other tissues

    1. Front Matter
      Pages 113-116
    2. Tim Hardingham
      Pages 131-146
    3. Mats Paulsson, Andreas R. Klatt, Birgit Kobbe, D. Patric Nitsche, Raimund Wagener
      Pages 151-158
    4. Thomas M. Schmid, Jui-Lan Su, Kathie M. Lindley, Vitaliy Soloveychik, Lawrence Madsen, Joel A. Block et al.
      Pages 159-161
    5. Frank Zaucke, Robert Dinser, Patrik Maurer, Mats Paulsson
      Pages 163-166
    6. Back Matter
      Pages 167-174
  5. Hyaluronan and joint biology

    1. Front Matter
      Pages 175-178
    2. Roger M. Mason, Peter J. Coleman, David Scott, J. Rodney Levick
      Pages 179-188
    3. Endre A. Balazs, Charles Weiss
      Pages 189-206
    4. Wannarat Yingsung, Lisheng Zhuo, Masahiko Yoneda, Naoki Ishiguro, Hisashi Iwata, Koji Kimata
      Pages 207-212
    5. Janet Y. Lee, Ryan B. Rountree, David M. Kingsley, Andrew P. Spicer
      Pages 213-218
    6. Cheryl B. Knudson, Kathleen T. Rousche, Richard S. Peterson, Geraldine Chow, Warren Knudson
      Pages 219-230
    7. Back Matter
      Pages 231-236
  6. Skeletal turnover in health and arthritis

    1. Front Matter
      Pages 237-239
    2. J. Frederick Woessner
      Pages 241-246
    3. Haya Ben-Zaken, Rosa Schneiderman, Hannah Kaufmann, Alice Maroudas
      Pages 247-252
    4. Wim B. van den Berg, Peter M. van der Kraan, Alwin Scharstuhl, Henk M. van Beuningen, Andrew Bakker, Peter L. E. M. van Lent et al.
      Pages 261-265
    5. Back Matter
      Pages 267-270
  7. From biomarkers to surrogate outcome measures in osteoarthritis

    1. Front Matter
      Pages 271-274
    2. David R. Eyre, Lynne M. Atley, Jiann-Jiu Wu
      Pages 275-284
    3. Tore Saxne, Dick Heinegård, Bengt Månsson
      Pages 285-292
    4. Thomas Aigner, Pia M. Gebhard, Alexander Zien
      Pages 293-296
    5. Ivan G. Otterness, Dolores Vázquez-Abad
      Pages 297-302
    6. Wolfgang Eger, Stefan Söder, Dietmar Thomas, Thomas Aigner, Günther Zeiler
      Pages 303-308
    7. Back Matter
      Pages 313-320
  8. Assessment of jOint damage in osteoarthritis

    1. Front Matter
      Pages 321-328
    2. Charles G. Peterfy
      Pages 329-350
    3. Carol Muehleman, Jürgen A. Mollenhauer, Matthias F. Aurich, Klaus E. Kuettner, Zhong Zhong, Ada Cole et al.
      Pages 351-354
    4. lain Watt
      Pages 355-362

About these proceedings


Osteoarthritis is the most common joint pathology which primarily affects the older population. The disease is characterized by unique pathological changes in some synovial joints, predominantly affecting the articular cartilage, but also entire joints, including the synovial tissue and subchondral bone.

The remarkable growth of research on normal and abnormal biology of tissues in the articulating joint, including the application of novel molecular biological approaches and new imaging techniques, is reflected in this volume. It describes the current state of knowledge and helps to further understand the etiopathology of osteoarthritis, hopefully leading to early detection of the disease and novel treatment modalities. The volume contains contributions and discussions from a select group of investigators, all experts in this field, who met at the conference "The Many Faces of Osteoarthritis", held in June 2001 at Lake Tahoe, to acknowledge Klaus E. Kuettner and his contributions to osteoarthritis research.

The book is a valuable source of information for researchers as well as for clinicians working in the fields of bone and joint surgery, tissue engineering, orthopaedics, rheumatology, and biomedicine.


Arthritis Epidemiology Inflammation Research Molecular Biology Therapy biomechanics imaging techniques immunology

Editors and affiliations

  • Vincent C. Hascall
    • 1
  • Klaus E. Kuettner
    • 2
  1. 1.Department of Biomedical Engineering, The Cleveland Clinic FoundationOrthopaedic Research CenterClevelandUSA
  2. 2.Department of BiochemistryRush Medical College at Rush Presbyterian-St. Luke’s Medical CenterChicagoUSA

Bibliographic information

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