© 2001

Genes and Mechanisms in Vertebrate Sex Determination

  • Gerd Scherer
  • Michael Schmid

Part of the Experientia Supplementum book series (EXS, volume 91)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Keith L. Parker, Bernard P. Schimmer, Andreas Schedl
    Pages 11-24
  3. Peter Koopman
    Pages 25-56
  4. Peter N. Goodfellow, Giovanna Camerino
    Pages 57-69
  5. Andrew Pask, Jennifer A. Marshall Graves
    Pages 71-95
  6. Claude Pieau, Mireille Dorizzi, Noëlle Richard-Mercier
    Pages 117-141
  7. Jean-François Baroiller, Yann Guiguen
    Pages 177-201
  8. Back Matter
    Pages 203-205

About this book


Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.


Chromosom Termination Vertebrate chromosome development fish genes mammals vertebrates

Editors and affiliations

  • Gerd Scherer
    • 1
  • Michael Schmid
    • 2
  1. 1.Institute of Human Genetics and AnthropologyUniversity of FreiburgFreiburgGermany
  2. 2.Department of Human GeneticsUniversity of WürzburgWürzburgGermany

Bibliographic information

  • Book Title Genes and Mechanisms in Vertebrate Sex Determination
  • Editors Gerd Scherer
    Michael Schmid
  • Series Title Experientia Supplementum
  • DOI
  • Copyright Information Birkhäuser Basel 2001
  • Publisher Name Birkhäuser, Basel
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-7643-6168-6
  • Softcover ISBN 978-3-0348-7783-1
  • eBook ISBN 978-3-0348-7781-7
  • Series ISSN 1023-294X
  • Edition Number 1
  • Number of Pages XII, 205
  • Number of Illustrations 36 b/w illustrations, 0 illustrations in colour
  • Topics Animal Genetics and Genomics
  • Buy this book on publisher's site
Industry Sectors