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The Resonant Recognition Model of Macromolecular Bioactivity

Theory and Applications

  • Irena Cosic
Book

Part of the BioMethods book series (BIOMETHODS)

Table of contents

  1. Front Matter
    Pages I-X
  2. Irena Cosic
    Pages XI-XII
  3. Irena Cosic
    Pages 1-9
  4. Irena Cosic
    Pages 11-30
  5. Irena Cosic
    Pages 31-45
  6. Irena Cosic
    Pages 89-111
  7. Irena Cosic
    Pages 113-130
  8. Irena Cosic
    Pages 131-134
  9. Back Matter
    Pages 135-147

About this book

Introduction

Biological processes in any living organism are based on selective interactions be­ tween particular biomolecules. In most cases, these interactions involve and are driven by proteins, which are the main conductors of any life process within the organism. The physical nature of these interactions is still not well known. This book presents an entirely new approach to analysis of biomolecular in­ teractions, in particular protein-protein and protein-DNA interactions, based on the assumption that these interactions are electromagnetic in nature. This new ap­ proach is the basis of the Resonant Recognition Model (RRM), which was devel­ oped over the last 15 years. Certain periodicities within the distribution of energies of delocalised electrons along a protein molecule are crucial to the protein's biological function, i.e. inter­ action with its target. If protein conductivity were introduced, then charges mov­ ing through the protein backbone might produce electromagnetic irradiation or ab­ sorption with spectral characteristics corresponding to energy distribution along the protein. The RRM is capable of calculating these spectral characteristics, which we hypothesized would be in the range of the infrared and visible light. These characteristics were confirmed with frequency characteristics obtained ex­ perimentally for certain light-induced biological processes.

Keywords

Biotechnology biochemistry chemistry molecular medicine protein proteins

Authors and affiliations

  • Irena Cosic
    • 1
  1. 1.Department of Electrical and Computer Systems EngineeringMonash UniversityCaulfield EastAustralia

Bibliographic information

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