© 2020

Developmental Neuroendocrinology

  • Susan Wray
  • Seth Blackshaw

Part of the Masterclass in Neuroendocrinology book series (MANEURO, volume 9)

Table of contents

  1. Front Matter
    Pages i-x
  2. Molecular Specification of Hypothalamic/Pituitary Cells

    1. Front Matter
      Pages 1-1
    2. Marysia Placzek, Travis Fu, Matthew Towers
      Pages 3-30
    3. Gonzalo Alvarez-Bolado
      Pages 31-66
    4. Nerea Moreno, Agustín González
      Pages 67-82
    5. Jae W. Lee, Christian Huisman, Seunghee Lee
      Pages 83-103
  3. Developmental Modulators and Epigenetic Factors

    1. Front Matter
      Pages 179-179
    2. M. Stratton, S. Tobet
      Pages 181-205
    3. Carlos Francisco Aylwin, Alejandro Lomniczi
      Pages 207-235
    4. Michela Pulix, Antonius Plagge
      Pages 265-294
    5. Christopher S. Coyle, Elisabetta Tolla, Tyler J. Stevenson
      Pages 295-314
  4. Development of Neuroendocrine Circuits

    1. Front Matter
      Pages 315-315
    2. Newton S. Canteras, Dayu Lin, Joshua G. Corbin
      Pages 317-343
    3. Lydia L. DonCarlos, Julie A. Chowen
      Pages 367-391
    4. Margaret M. McCarthy
      Pages 393-412
    5. Neta Gotlieb, Jacob Moeller, Lance J. Kriegsfeld
      Pages 413-446

About this book


In this book, experts in the field discuss the latest research in developmental neuroendocrinology.

Given that the hypothalamus is the center of neuroendocrine activity, the reader will learn about the molecular specification of hypothalamic cells, developmental modulators and epigenetic factors influencing hypothalamic development, and the development of neuroendocrine circuits. Each chapter provides a concise review of the current and future perspectives in developmental neuroendocrinology. Important insights into state-of-the-art techniques applied to functional circuit tracking, lineage tracing of hypothalamic cells, and the identification of genes altered through epigenetic mechanisms are also provided.

Given its scope, the book will appeal to all students and researchers who are eager to understand the processes involved in hypothalamus development and the establishment of neuroendocrine circuits.

This is the ninth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series* that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

*Volumes 1-7 published by Wiley.


Developmental Neuroendocrionology Hypothalamus Neuroendocrine Activity Neuroendocrine Circuits Peptidergic Systems

Editors and affiliations

  • Susan Wray
    • 1
  • Seth Blackshaw
    • 2
  1. 1.Cellular and Developmental NeurobiologyNINDS, NIHBethesdaUSA
  2. 2.Department of NeuroscienceSchool of Medicine, Johns Hopkins UniversityBaltimoreUSA

About the editors

Susan Wray received her B.A. from Middlebury College and her M.S. and Ph.D. from the University of Rochester School of Medicine and Dentistry, Department of Anatomy and Neurobiology. She joined Dr. Harold Gainer’s laboratory at the NICHD, NIH for her postdoctoral research, and in 1995 established her own section, Cellular and Developmental Neurobiology, at the NINDS, NIH. Her research focuses on the development and regulation of gonadotropin releasing hormone (GnRH) neurons, identifying their origin in the nasal placode and subsequent migration into the forebrain. Her work has bridged developmental issues including cell lineage, neuronal migration and craniofacial development with physiological issues such as functional GnRH neuronal subpopulations, the mechanisms regulating pulsatile secretion of GnRH, and causes of reproductive dysfunction.

Seth Blackshaw received his B.A. and M.S. in Biochemistry in 1991 and his PhD in Neuroscience from Johns Hopkins School of Medicine in 1997, working with Solomon Snyder.  He pursued postdoctoral research with Connie Cepko at Harvard Medical School, and in 2004 rejoined the Johns Hopkins School of Medicine, where he is now a Professor of Neuroscience.  His research has focused on the regulation of cell fate specification and neuronal regeneration in the retina and hypothalamus, hypothalamic regulation of innate behaviors, and the development of new tools for functional genomics and proteomics. 

Bibliographic information

  • Book Title Developmental Neuroendocrinology
  • Editors Susan Wray
    Seth Blackshaw
  • Series Title Masterclass in Neuroendocrinology
  • Series Abbreviated Title Masterclass in Neuroendocrinology
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-030-40001-9
  • Softcover ISBN 978-3-030-40004-0
  • eBook ISBN 978-3-030-40002-6
  • Series ISSN 2662-2068
  • Series E-ISSN 2662-2076
  • Edition Number 1
  • Number of Pages X, 468
  • Number of Illustrations 8 b/w illustrations, 77 illustrations in colour
  • Topics Neurosciences
    Internal Medicine
  • Buy this book on publisher's site
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