About this book
Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact.
Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles.
migration molecular mechanisms Molecular Motors Actin Filaments Cytoskeleton ATPases Intracellular Transport
Editors and affiliations
- DOI https://doi.org/10.1007/978-3-030-38062-5
- Copyright Information Springer Nature Switzerland AG 2020
- Publisher Name Springer, Cham
- eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
- Print ISBN 978-3-030-38061-8
- Online ISBN 978-3-030-38062-5
- Series Print ISSN 0065-2598
- Series Online ISSN 2214-8019
- Buy this book on publisher's site