Mucosal Delivery of Drugs and Biologics in Nanoparticles

  • Pavan Muttil
  • Nitesh K. Kunda

Part of the AAPS Advances in the Pharmaceutical Sciences Series book series (AAPS, volume 41)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Background

    1. Front Matter
      Pages 1-1
    2. Tejashri Chavan, Pavan Muttil, Nitesh K. Kunda
      Pages 3-26
    3. Kalpesh Vaghasiya, Ankur Sharma, Eupa Ray, Suneera Adlakha, Rahul Kumar Verma
      Pages 27-57
  3. Nanoparticle-Based Mucosal Delivery of Drugs and Biologics

    1. Front Matter
      Pages 59-59
    2. Kan Kaneko, Nashwa Osman, Valeria Carini, Giulia Scagnetti, Imran Saleem
      Pages 61-82
    3. Vineela Parvathaneni, Nishant S. Kulkarni, Vivek Gupta
      Pages 83-106
    4. Andrea C. Ortiz, Javier O. Morales
      Pages 107-124
    5. Joanne M. Ramsey, Alice McCloskey, Rachel Gaul, Elena Fernandez Fernandez, Louise Sweeney, Catherine M. Greene et al.
      Pages 125-154
    6. Rikhav P. Gala, Lotika Bajaj, Amit Bansal, Keegan Braz Gomes, Devyani Joshi, Ipshita Menon et al.
      Pages 155-175
    7. Achraf Noureddine, Jonas G. Croissant, Harrison O. Davis, Lorenza I. Friedrich, Rita E. Serda
      Pages 177-204
  4. Host Interactions with Nanoparticles

  5. Back Matter
    Pages 269-277

About this book


This book focuses on the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes.It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery. Mucosal Delivery of Drugs and Biologics in Nanoparticles emphasize the use of nanoparticles in treating various cancers and infectious diseases. It broadens the use of nanoparticles by including biologics, including vaccines and immunotherapies, apart from drugs. It acknowledges the concerns around the potential toxicity of nanoparticles to the host; few chapters will discuss the biodistribution of these nanoparticles when mucosal routes of administration are employed. Further, the interaction of nanoparticles with the host’s immune cells is discussed. Moreover,it reviews the regulatory aspects of nanotechnology in product development, especially when delivered by the mucosal route of administration. Lastly, discusses the challenges and opportunities to manufacture nanoparticles on an industrial scale. This book will be the first of its kind to focus on the design, development and delivery of nanoparticles when administered by different mucosal routes.


nanomedicine drugs and biologics nanoparticulate vaccines nano particle pharmacokinetics and pharmacodynamics theranostics nanoparticel manufacturing

Editors and affiliations

  • Pavan Muttil
    • 1
  • Nitesh K. Kunda
    • 2
  1. 1.Department of Pharmaceutical SciencesCollege Pharmacy, University of New MexicoAlbuquerqueUSA
  2. 2.Department of Pharmaceutical Sciences College of Pharmacy and Health SciencesSt. John’s UniversityJamaicaUSA

Bibliographic information

  • DOI
  • Copyright Information American Association of Pharmaceutical Scientists 2020
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-030-35909-6
  • Online ISBN 978-3-030-35910-2
  • Series Print ISSN 2210-7371
  • Series Online ISSN 2210-738X
  • Buy this book on publisher's site
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