© 2019

Concepts and Principles of Pharmacology

100 Years of the Handbook of Experimental Pharmacology

  • James E. Barrett
  • Clive P. Page
  • Martin C. Michel

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 260)

Table of contents

  1. Front Matter
    Pages i-viii
  2. James E. Barrett, Clive Page, Martin C. Michel
    Pages 3-16
  3. Terry Kenakin
    Pages 17-41
  4. Madeha Khan, James Spicer
    Pages 43-79
  5. J. Posner, P. Barrington, T. Brier, A. Datta-Mannan
    Pages 81-141
  6. Federico Lavorini, Francesca Buttini, Omar S. Usmani
    Pages 143-159
  7. Francesco De Logu, Pierangelo Geppetti
    Pages 161-186
  8. Irene Mollinedo-Gajate, Chenchen Song, Thomas Knöpfel
    Pages 209-229
  9. Denis Menshykau, Simon Tanaka
    Pages 231-261
  10. Aries Chavira, Pedro Belda-Ferre, Tomasz Kosciolek, Farhana Ali, Pieter C. Dorrestein, Rob Knight
    Pages 301-326
  11. D. Lansing Taylor, Albert Gough, Mark E. Schurdak, Lawrence Vernetti, Chakra S. Chennubhotla, Daniel Lefever et al.
    Pages 327-367
  12. Matthijs D. Kruizinga, Frederik E. Stuurman, Geert J. Groeneveld, Adam F. Cohen
    Pages 371-397
  13. Paul Enck, Sibylle Klosterhalfen
    Pages 399-431
  14. Nicholas Moore, Patrick Blin, Cécile Droz
    Pages 433-451
  15. Basma Hammel, Martin C. Michel
    Pages 453-466

About this book


Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.


History Nobel prize biased agonism allosteric modulation immunopharmacology monoclonal antibodies siRNA ion channel metabolomics pharmacogenomics microbiome placebo optogenetics organ on a chip drug delivery natural products trial design

Editors and affiliations

  • James E. Barrett
    • 1
  • Clive P. Page
    • 2
  • Martin C. Michel
    • 3
  1. 1.Center for Substance Abuse ResearchLewis Katz School of Medicine at Temple UniversityPhiladelphiaUSA
  2. 2.Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical ScienceKing’s College LondonLondonUK
  3. 3.Department of PharmacologyJohannes Gutenberg UniversityMainz, Rheinland-PfalzGermany

Bibliographic information

  • Book Title Concepts and Principles of Pharmacology
  • Book Subtitle 100 Years of the Handbook of Experimental Pharmacology
  • Editors James E. Barrett
    Clive P. Page
    Martin C. Michel
  • Series Title Handbook of Experimental Pharmacology
  • Series Abbreviated Title Hdb Exp.Pharmacology(formerly:Starke,K.:Eds)
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-030-35361-2
  • Softcover ISBN 978-3-030-35364-3
  • eBook ISBN 978-3-030-35362-9
  • Series ISSN 0171-2004
  • Series E-ISSN 1865-0325
  • Edition Number 1
  • Number of Pages VIII, 466
  • Number of Illustrations 70 b/w illustrations, 30 illustrations in colour
  • Topics Pharmacology/Toxicology
  • Buy this book on publisher's site
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