Prostate Cancer

Cellular and Genetic Mechanisms of Disease Development and Progression

  • Scott M. Dehm
  • Donald J. Tindall

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1210)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Kathryn M. Wilson, Lorelei A. Mucci
    Pages 1-27
  3. Medjda Bellamri, Robert J. Turesky
    Pages 29-55
  4. Michael Fraser, Alexandre Rouette
    Pages 87-110
  5. Daniel E. Spratt
    Pages 111-120
  6. Nataliya Prokhnevska, Dana A. Emerson, Haydn T. Kissick, William L. Redmond
    Pages 121-147
  7. William L. Harryman, Noel A. Warfel, Raymond B. Nagle, Anne E. Cress
    Pages 149-170
  8. Anthony DiNatale, Alessandro Fatatis
    Pages 171-184
  9. Chenchu Lin, Travis C. Salzillo, David A. Bader, Sandi R. Wilkenfeld, Dominik Awad, Thomas L. Pulliam et al.
    Pages 185-237
  10. Karl-Heinz Storbeck, Elahe A. Mostaghel
    Pages 239-277
  11. Sara Arce, Alejandro Athie, Colin C. Pritchard, Joaquin Mateo
    Pages 279-300
  12. Deborah L. Burkhart, Katherine L. Morel, Anjali V. Sheahan, Zachary A. Richards, Leigh Ellis
    Pages 301-318
  13. Aashi P. Chaturvedi, Scott M. Dehm
    Pages 333-350
  14. Yunshin Yeh, Qiaozhi Guo, Zachary Connelly, Siyuan Cheng, Shu Yang, Nestor Prieto-Dominguez et al.
    Pages 351-378
  15. Ramakrishnan Natesan, Shweta Aras, Samuel Sander Effron, Irfan A. Asangani
    Pages 379-407
  16. Taylor R. Nicholas, Brady G. Strittmatter, Peter C. Hollenhorst
    Pages 409-436
  17. Daksh Thaper, Sepideh Vahid, Amina Zoubeidi
    Pages 437-462
  18. Back Matter
    Pages 463-476

About this book


The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis.

Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.


cancer research cell-cell interactions prostate cancer stem cells Signaling Metabolism

Editors and affiliations

  • Scott M. Dehm
    • 1
  • Donald J. Tindall
    • 2
  1. 1.Department of Laboratory Medicine and Pathology, Department of UrologyMasonic Cancer Center, University of MinnesotaMinneapolisUSA
  2. 2.Departments of Urology, and Biochemistry & Molecular BiologyMayo Clinic College of MedicineRochesterUSA

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods