Advertisement

3D Bioprinting

Modeling In Vitro Tissues and Organs Using Tissue-Specific Bioinks

  • Dong-Woo Cho
  • Byoung Soo Kim
  • Jinah Jang
  • Ge Gao
  • Wonil Han
  • Narendra K. Singh
Textbook

Table of contents

  1. Front Matter
    Pages i-xv
  2. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 1-4
  3. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 5-12
  4. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 13-23
  5. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 25-29
  6. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 31-40
  7. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 41-51
  8. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 53-108
  9. Dong-Woo Cho, Byoung Soo Kim, Jinah Jang, Ge Gao, Wonil Han, Narendra K. Singh
    Pages 109-110
  10. Back Matter
    Pages 111-114

About this book

Introduction

The volume offers a fundamental knowledgein modeling in vitro tissues/organs as an alternative to 2D cell culture and animal testing. Prior to engineering in vitro tissues/organs,the descriptions of prerequisites (from pre-processing to post-processing) in modeling in vitro tissues/organs are discussed. The most prevalent technologies that have been widely used for establishing the in vitro tissue/organ models are also described, including transwell, cell spheroids/sheets, organoids, and microfluidic-based chips. In particular, the authors focus on 3D bioprintingin vitro tissue/organ models using tissue-specific bioinks. Several representative bioprinting methods and conventional bioinks are introduced. As a bioink source,decellularized extracellular matrix (dECM) are importantly covered, including decellularization methods, evaluation  methods  for demonstrating successful decellularization, and material safety. Taken together, the authors delineate various application examples of 3D bioprintedin vitro tissue/organ models especially using dECM bioinks. This book may provide an introductory guide for modeling in vitro tissues/organs and for opening up agate for beginnersincluding teachers and undergraduate/graduate students.
-Provides strategic insight into the biofabrication of in vitro tissues and organs;
-Introduces 3D cell-printing techniques and dECM-based bioinks;
-Includes examples of 3D cell printed in vitro tissues/organs.

Keywords

3D printing 3D cell printing Bioinks Biofabrication Biomaterials Cell Biology Decellularized extracellular matrix dECM In vitro organ biofabrication In vitro organ modeling In vitro tissue biofabrication In vitro tissue modeling Organ-on-chips Organoids Tissue engineering

Authors and affiliations

  • Dong-Woo Cho
    • 1
  • Byoung Soo Kim
    • 2
  • Jinah Jang
    • 3
  • Ge Gao
    • 4
  • Wonil Han
    • 5
  • Narendra K. Singh
    • 6
  1. 1.Department of Mechanical Engineering and Division of Integrative Biosciences and BiotechnologyPohang University of Science and TechnologyPohangKorea (Republic of)
  2. 2.Future IT Innovation LaboratoryPohang University of Science and TechnologyPohangKorea (Republic of)
  3. 3.Department of Creative IT Engineering and Mechanical EngineeringPohang University of Science and TechnologyPohangKorea (Republic of)
  4. 4.Department of Mechanical EngineeringPohang University of Science and TechnologyPohangKorea (Republic of)
  5. 5.Division of Integrative Biosciences and BiotechnologyPohang University of Science and TechnologyPohangKorea (Republic of)
  6. 6.Department of Mechanical EngineeringPohang University of Science and TechnologyPohangKorea (Republic of)

Bibliographic information

Industry Sectors
Biomedicine
Pharma
Biotechnology
Surgery & Anesthesiology
Orthopedics
Consumer Packaged Goods
Engineering