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© 2020

Precision in Pulmonary, Critical Care, and Sleep Medicine

A Clinical and Research Guide

  • Jose L. Gomez
  • Blanca E. Himes
  • Naftali Kaminski
Book

Part of the Respiratory Medicine book series (RM)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Jose L. Gomez, Naftali Kaminski, Blanca E. Himes
      Pages 3-8
  3. Genetics

    1. Front Matter
      Pages 9-9
    2. Mengyuan Kan, Blanca E. Himes
      Pages 25-37
    3. Yohan Bossé, Michael H. Cho
      Pages 39-55
    4. Yukiko Kunitomo, Clemente J. Britto
      Pages 57-69
    5. Susan K. Mathai, David A. Schwartz
      Pages 71-85
    6. Katrina Steiling, Joshua D. Campbell
      Pages 87-103
  4. Biomarkers

    1. Front Matter
      Pages 105-105
    2. Samuel Y. Ash, Raúl San José Estépar, George R. Washko
      Pages 107-115
    3. Julia Winkler, Erica L. Herzog
      Pages 117-130
    4. Rachel S. Kelly, Kathleen A. Stringer, Chris H. Wendt
      Pages 131-153
    5. Isis E. Fernandez, Oliver Eickelberg
      Pages 155-165
    6. Catherine A. Gao, John C. Huston, Patricia Valda Toro, Samir Gautam, Charles S. Dela Cruz
      Pages 167-184
    7. Simon P. F. Lambden, Charlotte Summers
      Pages 185-198
  5. Precise Phenotyping

    1. Front Matter
      Pages 199-199
    2. Brett C. Bade, Finbar T. Foley, Lynn T. Tanoue
      Pages 201-223
    3. Emmet O’Brien, Frank C. Sciurba, Jessica Bon
      Pages 225-239

About this book

Introduction

This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans.

 

Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles derived from population studies. This concept has risen to prominence in recent years in parallel with advances in genetics, molecular diagnostics and novel target-specific therapies. This fundamental shift in the approach to treatment has broad implications in how we prevent, diagnose and treat disease. Describing key concepts of precision medicine and relating these to pulmonary, critical care and sleep disorders is essential to educate relevant stakeholders and increase the impact of pulmonary precision medicine.

                 

The book is organized into seven sections: introduction; genetics; biomarkers; precise phenotyping; mobile health, wearables and telemedicine; precision therapeutics; and enabling widespread adoption of precision medicine. The chapters are organized with an introduction to the specific theme, followed by its basic concepts. They then delve into how these basic concepts relate to the larger theme of precision medicine, new precision medicine approaches to dealing with these problems, and key takeaway points. Liberally illustrated with images, figures, and tables, the text is thorough and intuitive for clinicians and researchers to learn the processes and applications of precision medicine.

 

This is an ideal guide for clinicians to learn new precision medicine concepts in the fields of genetics, genomics, mobile health, and how they apply to their practice and their patients, as well as researchers seeking a basic understanding of precision medicine to assist in designing future research studies. 

Keywords

precision medicine pulmonary medicine pulmonology critical care sleep medicine omics genetics phenotyping

Editors and affiliations

  • Jose L. Gomez
    • 1
  • Blanca E. Himes
    • 2
  • Naftali Kaminski
    • 3
  1. 1.Assistant Professor Pulmonary, Critical Care and Sleep Medicine Section, Department of MedicineYale University School of MedicineNew HavenUSA
  2. 2.Assistant Professor of Informatics, Department of Biostatistics, Epidemiology and InformaticsUniversity of PennsylvaniaPhiladelphiaUSA
  3. 3.Boehringer-Ingelheim Endowed, Professor of Internal Medicine, Chief of Pulmonary, Critical Care and Sleep MedicineYale University School of MedicineNew HavenUSA

About the editors

Jose L. Gomez, MD, MS, ATSF

Assistant Professor

Pulmonary, Critical Care and Sleep Medicine Section

Department of Medicine

Yale University School of Medicine

New Haven, CT, USA


Blanca E. Himes, PhD

Assistant Professor of Informatics

Department of Biostatistics, Epidemiology and Informatics

University of Pennsylvania

Philadelphia, PA, USA


Naftali Kaminski, MD, FERS, ATSF

Boehringer-Ingelheim Endowed Professor of Internal Medicine

Chief of Pulmonary, Critical Care and Sleep Medicine

Department of Medicine

Yale University School of Medicine

New Haven, CT, USA

Bibliographic information

  • Book Title Precision in Pulmonary, Critical Care, and Sleep Medicine
  • Book Subtitle A Clinical and Research Guide
  • Editors Jose L. Gomez
    Blanca E. Himes
    Naftali Kaminski
  • Series Title Respiratory Medicine
  • Series Abbreviated Title Respiratory Medicine
  • DOI https://doi.org/10.1007/978-3-030-31507-8
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Humana, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-030-31506-1
  • Softcover ISBN 978-3-030-31509-2
  • eBook ISBN 978-3-030-31507-8
  • Series ISSN 2197-7372
  • Series E-ISSN 2197-7380
  • Edition Number 1
  • Number of Pages XV, 441
  • Number of Illustrations 8 b/w illustrations, 63 illustrations in colour
  • Topics Pneumology/Respiratory System
    Intensive / Critical Care Medicine
  • Buy this book on publisher's site
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