© 2020

Therapy Response Imaging in Oncology

  • Mizuki Nishino

Part of the Medical Radiology book series (MEDRAD)

Also part of the Diagnostic Imaging book sub series (Med Radiol Diagn Imaging)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Imaging as a “Common Language” for Treatment Response Evaluations in Oncology

  3. Practical Pitfalls in Therapy Response Imaging in Cancer Patients

  4. Part III

    1. Front Matter
      Pages 45-45
    2. Peter Abraham, Jason Handwerker
      Pages 47-63
    3. Masako Kataoka
      Pages 65-78
    4. Sanaz Ameli, Mohammadreza Shaghaghi, Ihab R. Kamel, Atif Zaheer
      Pages 117-137
    5. Katherine M. Krajewski
      Pages 139-157
  5. Emerging Approaches and Future Directions

    1. Front Matter
      Pages 219-219
    2. Geewon Lee, So Hyeon Bak, Ho Yun Lee, Joon Young Choi, Hyunjin Park
      Pages 221-238
    3. Amy Junghyun Lee, Chong Hyun Suh, Kyung Won Kim
      Pages 239-253
    4. Katherine A. Zukotynski, Phillip H. Kuo, Chun K. Kim, Rathan M. Subramaniam
      Pages 255-272

About this book


This book is a detailed guide to therapy response imaging in cancer patients that fully takes into account the revolutionary progress and paradigm shift in treatment approaches for advanced disease. The opening chapters describe the role of imaging as a “common language” for tumor response evaluation in oncology and address challenges and strategies in the era of precision cancer therapy and cancer immunotherapy. Practical pitfalls are discussed, with emphasis on the importance of approaching cancer as a systemic disease and the need for increased awareness of drug toxicity due to novel therapies. Therapy response imaging in a wide range of cancer types is then comprehensively described and illustrated, using a disease-specific approach. A concluding section focuses on emerging approaches and future directions, including radiomics/radiogenomics, co-clinical imaging, and molecular and functional imaging. Therapy Response Imaging in Oncology will be of high value for radiologists, nuclear medicine physicians, and oncologists. It will also be of interest to cancer care providers and oncology trial investigators.


Tumor response evaluation in oncology Oncologic imaging Tumor response assessment Precision medicine Cancer Immunotherapy Positron emission tomography Precision cancer therapy and immunotherapy Radiogenomics for tumor response evaluations Co-clinical imaging in oncology Radiomics for tumor response evaluations

Editors and affiliations

  • Mizuki Nishino
    • 1
  1. 1.Dana-Farber Cancer Institute and Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA

About the editors

Mizuki Nishino is a diagnostic radiologist specialized in oncologic imaging, with a particular focus on therapy response imaging in the setting of precision cancer therapy and cancer immunotherapy. Dr. Nishino is a fellowship-trained thoracic radiologist. Her research has focused on therapy response imaging in lung cancer treated with molecular targeting therapy, contributing to the identification of objective imaging markers to predict treatment benefit and clinical outcome. Dr. Nishino has also applied her expertise to therapy response imaging in cancer immunotherapy and has published a series of fundamental studies to refine strategies for immune-related response evaluation. In addition she has made contributions to imaging-based characterization of drug toxicities in cancer patients treated with precision therapy and immunotherapy. Dr. Nishino published the first report of clinical and imaging characteristics of immune checkpoint inhibitor-related pneumonitis, defined the spectrum of radiographic manifestations of the entity, and continues to work on the topic to develop strategies for early detection and accurate diagnosis.

Bibliographic information

  • Book Title Therapy Response Imaging in Oncology
  • Editors Mizuki Nishino
  • Series Title Medical Radiology
  • Series Abbreviated Title Medical Radiology
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-030-31170-4
  • Softcover ISBN 978-3-030-31173-5
  • eBook ISBN 978-3-030-31171-1
  • Series ISSN 0942-5373
  • Series E-ISSN 2197-4187
  • Edition Number 1
  • Number of Pages VIII, 272
  • Number of Illustrations 79 b/w illustrations, 52 illustrations in colour
  • Topics Diagnostic Radiology
  • Buy this book on publisher's site
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