Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics

  • Kevin M. Koo

Part of the Springer Theses book series (Springer Theses)

About this book


This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.


Prostate Cancer Detection Precision Medicine Urinary Nanodiagnostics Clinical Translation Biosensor Development Next-generation Prostate Cancer Biomarkers Non-invasive Prostate Cancer Nanodiagnostics TMPRSS2–ETS Fusion Genes Electro Chemistry Surface-enhanced Raman spectroscopy Enhanced Detection Performance Nanodiagnostics for Clinical Applications Lab-in-a-drop Fluidic Mixing

Authors and affiliations

  • Kevin M. Koo
    • 1
  1. 1.Australian Institute for Bioengineering and Nanotechnology, The University of QueenslandBrisbaneAustralia

Bibliographic information

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