Uncertainty in Pharmacology

Epistemology, Methods, and Decisions

  • Adam LaCaze
  • Barbara Osimani

Part of the Boston Studies in the Philosophy and History of Science book series (BSPS, volume 338)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Epistemology

  3. Methods

  4. Decisions

    1. Front Matter
      Pages 373-373
    2. Sven Ove Hansson
      Pages 375-396
    3. Miriam Solomon
      Pages 439-450

About this book


This volume covers a wide range of topics concerning methodological, epistemological, and regulatory-ethical issues around pharmacology. The book focuses in particular on the diverse sources of uncertainty, the different kinds of uncertainty that there are, and the diverse ways in which these uncertainties are (or could be) addressed. Compared with the more basic sciences, such as chemistry or biology, pharmacology works across diverse observable levels of reality: although the first step in the causal chain leading to the therapeutic outcome takes place at the biochemical level, the end-effect is a clinically observable result—which is influenced not only by biological actions, but also psychological and social phenomena. Issues of causality and evidence must be treated with these specific aspects in mind. In covering these issues, the book opens up a common domain of investigation which intersects the deeply intertwined dimensions of pharmacological research, pharmaceutical regulation and the related economic environment. The book is a collective endeavour with in-depth contributions from experts in pharmacology, philosophy of medicine, statistics, scientific methodology, formal and social epistemology, working in constant dialogue across disciplinary boundaries.


Drug Development Drug Policy Drug Safety Clinical Trials Risk Prevention Pharmaceutical Market Pharmaceutical Regulation Health Policies Statistics in Pharmacology Systems Pharmacology Bayesian Statistics in Pharmacology

Editors and affiliations

  • Adam LaCaze
    • 1
  • Barbara Osimani
    • 2
  1. 1.School of PharmacyThe University of QueenslandSt LuciaAustralia
  2. 2.Department of Biomedical Sciences and Public Health, Polytechnic University of the Marche, Ancona, ItalyMunich Center for Mathematical Philosophy, Munchen, LMUMunichGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Religion and Philosophy
  • Print ISBN 978-3-030-29178-5
  • Online ISBN 978-3-030-29179-2
  • Series Print ISSN 0068-0346
  • Series Online ISSN 2214-7942
  • Buy this book on publisher's site