Table of contents
Basics of Genetics
Endocrine Diseases Inherited as Monogenic Traits: Hormone Resistance Syndromes
Endocrine Diseases Inherited as Monogenic Traits: Hereditary Diseases Predisposing to Endocrine Tumors
Endocrine Diseases Inherited as Monogenic Traits: Monogenic Diseases Predisposing to Hormone Deficiency, Infertility and Diabetes Mellitus
Example of a Multifactorial Disease and Chromosomal Alterations in Endocrine Diseases
About this book
This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. It covers both the molecular and clinical consequences of these genetic defects, as well as the relevance for clinical care, highlighting issues of genetic counseling.
Several endocrine diseases have a genetic background, and contemporary research in the field plays a crucial role in the clinical care of endocrine diseases. In recent years, there have been major developments in our understanding of the genetic basis of endocrine diseases. Several novel genes and mutations predisposing individuals to monogenic endocrine diseases have been discovered, and with the advent of next generation sequencing, a huge amount of new data has become available. Further, novel molecular mechanisms, such as genomic imprinting, have been implicated in the pathogenesis of endocrine diseases.
A better understanding of the genetic background of these diseases is relevant not only from the research perspective, but also in terms of clinical care. As such, this book is an essential read for both researchers and clinicians working in the field.
Editors and affiliations
- DOI https://doi.org/10.1007/978-3-030-25905-1
- Copyright Information Springer Nature Switzerland AG 2019
- Publisher Name Springer, Cham
- eBook Packages Biomedical and Life Sciences
- Print ISBN 978-3-030-25904-4
- Online ISBN 978-3-030-25905-1
- Series Print ISSN 1664-431X
- Series Online ISSN 2504-3692
- Buy this book on publisher's site