Colorectal Cancer Liver Metastases

A Comprehensive Guide to Management

  • Mauro Monteiro Correia
  • Michael A. Choti
  • Flavio G. Rocha
  • Go Wakabayashi

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Carlos Eduardo Rodrigues Santos, Mauro Monteiro Correia
    Pages 1-6
  3. Mathew M. Augustine
    Pages 7-20
  4. Malcolm H. Squires III, Jordan M. Cloyd, Timothy M. Pawlik
    Pages 21-34
  5. Roberto Heleno Lopes, Bruno Roberto Braga Azevedo, André Noronha Arvellos, Phillipe Abreu-Reis, Alexandre Ferreira Oliveira
    Pages 35-48
  6. Khalid W. Shaqdan, Ali Pourvaziri, Dushyant V. Sahani
    Pages 49-64
  7. Toru Beppu, Go Wakabayashi, Katsunori Imai, Yasushi Yoshida, Hideo Baba
    Pages 65-85
  8. Felipe José Fernández Coimbra, Paulo Henrique Miranda Brandão, Alessandro Landskron Diniz, Heber Salvador de Castro Ribeiro, Wilson Luiz da Costa Júnior, André Luiz de Godoy et al.
    Pages 87-94
  9. Camille Stewart, Yuman Fong
    Pages 95-111
  10. Ibrahim Nassour, Michael A. Choti
    Pages 113-117
  11. Orlando Jorge Martins Torres, Marcos Belotto de Oliveira, Paulo Cezar Galvão do Amaral, Eliza Dalsasso Ricardo, Agnaldo Soares Lima, Alexandre Prado de Resende et al.
    Pages 145-157
  12. Kimberly A. Bertens, Jad Abou Khalil, Guillaume Martel
    Pages 159-172
  13. Bhavana P. Singh, Benjamin A. Weinberg, Sunnie S. Kim, John L. Marshall
    Pages 185-203
  14. Georgios Karagkounis, Michael A. Choti
    Pages 229-238
  15. Mariana Bruno Siqueira, João Paulo Fogacci, Roberto de Almeida Gil, Mauro Monteiro Correia
    Pages 239-247
  16. Carlos José Coelho de Andrade
    Pages 249-258
  17. Vitor Moutinho, Louise C. Connell, Nancy Kemeny
    Pages 283-296
  18. Marc T. Roth, Laura W. Goff
    Pages 297-312
  19. Eve Simoneau, Thomas A. Aloia, Ching-Wei D. Tzeng
    Pages 329-343
  20. Rinaldo Gonçalves, Marcus Valadão, Rodrigo Araújo
    Pages 345-354
  21. Fábio Luiz Waechter, Uirá Fernandes Teixeira, Pablo Duarte Rodrigues, Marcio Boff, Rinaldo Danesi, Mauro Monteiro Correia
    Pages 355-369
  22. Giammauro Berardi, Go Wakabayashi
    Pages 371-384
  23. Eric C. H. Lai, Chung Ngai Tang
    Pages 385-395
  24. Mauro Monteiro Correia
    Pages 397-411
  25. Georgios Antonios Margonis, Matthew J. Weiss
    Pages 413-428
  26. Adriana C. Gamboa, Shishir K. Maithel
    Pages 429-444
  27. Marcus Valadão, Rinaldo Gonçalves, Rodrigo Araújo, Roberto de Almeida Gil
    Pages 445-453
  28. Jaime A. P. Krüger, Paulo Herman
    Pages 455-468
  29. Kerollos Nashat Wanis, Bao Tram Nghiem, Roberto Hernandez-Alejandro
    Pages 469-486
  30. Mariana I. Chavez, Christopher Coon, T. Clark Gamblin
    Pages 487-506
  31. José Hugo Mendes Luz
    Pages 507-518
  32. Rehan Ali, Ahmed Gabr, Ronald Mora, Ahsun Riaz, Robert Lewandowski
    Pages 519-529
  33. Pål-Dag Line, Morten Hagness, Svein Dueland
    Pages 531-546
  34. Raquel Guimarães Domingos da Silva, M. Carmen Rubio Rodriguez
    Pages 547-560
  35. Blaire Anderson, Ryan C. Fields
    Pages 571-587
  36. Back Matter
    Pages 589-598

About this book


Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. 

 The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. 

This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). 

 Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. 

This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.


Colorectal Liver Metastases Metastasis Prognostic factors Multidisciplinary team Chemotherapy Immunotherapy Surgery Ablation Hepatology

Editors and affiliations

  • Mauro Monteiro Correia
    • 1
  • Michael A. Choti
    • 2
  • Flavio G. Rocha
    • 3
  • Go Wakabayashi
    • 4
  1. 1.National Cancer InstituteRio de JaneiroBrazil
  2. 2.Banner MD Anderson Cancer CenterPhoenixUSA
  3. 3.Virginia Mason Medical CenterSeattleUSA
  4. 4.Center for Advanced Treatment of HBP Diseases, Ageo Central General HospitalAgeo Shi, SaitamaJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-030-25485-8
  • Online ISBN 978-3-030-25486-5
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology