© 2019

The Handbook of Cuffless Blood Pressure Monitoring

A Practical Guide for Clinicians, Researchers, and Engineers

  • Josep Solà
  • Ricard Delgado-Gonzalo
  • Provides a comprehensive overview of cuffless blood pressure monitoring

  • Covers physiological and technological concepts required to understand cuffless blood pressure monitoring

  • Reviews groundbreaking, state-of-the-art technologies, such as deep learning techniques for cuffless blood pressure monitoring


Table of contents

  1. Front Matter
    Pages i-xii
  2. Alberto Avolio, Fatemeh Shirbani, Isabella Tan, Mark Butlin
    Pages 1-7
  3. Audrey Adji, Michael F. O’Rourke
    Pages 15-30
  4. Marshal S. Dhillon, Matthew J. Banet
    Pages 43-59
  5. Jim Li
    Pages 61-73
  6. Martin C. Baruch
    Pages 75-105
  7. Martin Proença, Philippe Renevey, Fabian Braun, Guillaume Bonnier, Ricard Delgado-Gonzalo, Alia Lemkaddem et al.
    Pages 107-137
  8. Xiaorong Ding
    Pages 139-162
  9. Ramakrishna Mukkamala, Jin-Oh Hahn
    Pages 163-190
  10. Back Matter
    Pages 231-239

About this book


This book is the first comprehensive overview of the emerging field of cuffless blood pressure monitoring. Increasing clinical evidence proves that longitudinal measurements of blood pressure allow for earlier detection and better management of multiple medical conditions and for superior prediction of cardiovascular events. Unfortunately, today’s clinical and industry standards for blood pressure monitoring still require the inflation of a pneumatic cuff around a limb each time a measurement is taken. Over the last decades clinicians, scientists and device manufacturers have explored the feasibility of technologies that reduce or even completely eliminate the need of cuffs, initiating the era of cuffless blood pressure monitoring. Among the existing literature, this book is intended to be a practical guide to navigate across this emerging field. The chapters of the handbook have been elaborated by experts and key opinion leaders in the domain, and will guide the reader along the clinical, scientific, technical, and regulatory aspects of cuffless blood pressure monitoring.


Cuffless Blood Pressure Monitoring Non-invasive Blood Pressure Monitoring Electrocardiography Photoplethysmogram Pulse Transit Time Pulse Arrival Time Computational biology cuffless BP monitoring strategies Calibration cuffless BP monitors Standardization cuffless BP monitoring classification cuffless BP monitoring clinical trials cuffless BP trends cuffless BP monitoring

Editors and affiliations

  • Josep Solà
    • 1
  • Ricard Delgado-Gonzalo
    • 2
  1. 1.Aktiia SANeuchâtelSwitzerland
  2. 2.Swiss Center for Electronics and Microtechnology (CSEM, Centre Suisse d’Electronique et de Microtechnique)NeuchâtelSwitzerland

About the editors

Josep Solà

Passionate about the intersection of engineering and clinical work, Josep has spent 15 years doing research and development in the field of cuffless blood pressure monitoring. He graduated as a signal processing engineer at the Catalonia Polytechnic University (UPC), then completed his Master's Thesis at Sony International in Germany, before ultimately arriving in Switzerland in 2004 at the Swiss Center for Electronics and Microtechnogy (CSEM). At that time the Swiss institute was revolutionizing the field of wearable monitoring by showcasing the first measurements of Heart Rate at the wrist via optical sensors in motion. Interested in signal processing problems for non-invasive cardiovascular monitoring, he started exploring and benchmarking sensing modalities that could potentially lead to more widespread use of cuffless blood pressure devices. His research covered hybrid uses of Photo-Plethysmograhy (PPG), Electro-Cardiography (ECG), Impedance Cardiography (ICG), Phono-Cardiography (PCG) and Electrical Impedance Tomography (EIT). In 2012 he completed his PhD thesis at the Swiss Federal Institute of Technology in Zurich (ETHZ), titled “Continuous blood pressure monitoring.” He then focused all his efforts on how PPG sensing could be upgraded to provide clinically valuable blood pressure determinations in real life scenarios. In 2018 he co-founded Aktiia, a tech company that aims at bringing blood pressure monitoring to daily life.

Ricard Delgado-Gonzalo is the principal research scientist leading the Digital Health activity at the Swiss Center for Electronics and Microtechnology (CSEM). Trained as a Mathematician and as an Engineer at the Polytechnic University of Catalonia (UPC), he obtained his Ph.D. on biomedical image analysis from the Swiss Federal Institute of Technology in Lausanne (EPFL) within the consortium, the Swiss research initiative for the promotion of Systems Biology. He was awarded with the SSBE Research Award 2013 from the Swiss Society of Biomedical Engineering for the best PhD thesis, and the ABB Award 2014 for his “contributions to the field of bioimage informatics.” His current research focuses on AI applied to biomedical embedded systems, wearable technology, and their impact on the future of healthcare and the MedTech industry with more than 40 scientific publications on the topic.

Bibliographic information

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