The Drosophila Model in Cancer

  • Wu-Min Deng

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1167)

Table of contents

  1. Front Matter
    Pages i-vi
  2. Deeptiman Chatterjee, Wu-Min Deng
    Pages 1-14
  3. Santiago Nahuel Villegas, Dolors Ferres-Marco, María Domínguez
    Pages 15-35
  4. Natasha Fahey-Lozano, John E. La Marca, Marta Portela, Helena E. Richardson
    Pages 37-64
  5. Royjar Khezri, Tor Erik Rusten
    Pages 113-127
  6. Xiao Li, Mengmeng Liu, Jun-Yuan Ji
    Pages 129-155
  7. Moritz Sander, Héctor Herranz
    Pages 157-173
  8. Shree Ram Singh, Poonam Aggarwal, Steven X. Hou
    Pages 175-190
  9. Pedro Saavedra, Norbert Perrimon
    Pages 191-205
  10. Alexander S. Chen, Renee D. Read
    Pages 207-224
  11. Back Matter
    Pages 249-250

About this book


This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics.  Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression.


Readers will discover the beauty of the fly model’s genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use.  This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems.


This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.


oncogenes tumor suppressor signaling pathways cancer models drosophila model

Editors and affiliations

  • Wu-Min Deng
    • 1
  1. 1.Department of Biochemistry and Molecular BiologyTulane Cancer Center, LCRC, Tulane University School of MedicineNew OrleansUSA

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