Heat Shock Protein 90 in Human Diseases and Disorders

  • Alexzander A. A. Asea
  • Punit Kaur

Part of the Heat Shock Proteins book series (HESP, volume 19)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Oncogenic Aspects of HSP90

    1. Front Matter
      Pages 1-1
    2. Takanori Eguchi, Kisho Ono, Kazumi Kawata, Kuniaki Okamoto, Stuart K. Calderwood
      Pages 3-17
    3. Reyhaneh Moradi-Marjaneh, Seyed Mahdi Hassanian, Gordon A. Ferns, Amir Avan, Majid Khazaei
      Pages 47-84
    4. B. V. Sunil Kumar, Priya K. Gopal, Ramneek Verma
      Pages 103-124
    5. Geraldine O’Sullivan Coyne, Cecilia Monge, Alice P. Chen
      Pages 125-143
    6. Amr Ghaleb, Natalia Marchenko
      Pages 145-158
    7. Asmaa Aboelnour, Ahmed E. Noreldin, Islam M. Saadeldin
      Pages 183-200
    8. Timothy Westlake, Mitchell Sun, Brandon C. Rosenblum, Zhengping Zhuang, Jared S. Rosenblum
      Pages 201-215
    9. P. L. Abreu, L. M. R. Ferreira, T. Cunha-Oliveira, M. C. Alpoim, A. M. Urbano
      Pages 217-247
  3. Biomolecular Aspects of HSP90

    1. Front Matter
      Pages 249-249
    2. Chang Chen, Constance Jeffery
      Pages 269-279
    3. Chrisostomos Prodromou
      Pages 297-316
    4. Yohei Niikura, Katsumi Kitagawa
      Pages 317-370
  4. HSP90 in Natural Products Development

    1. Front Matter
      Pages 385-385
    2. Athanasia Warnecke, Andreas Kirschning, Daniel Landsberg, Carsten Zeilinger
      Pages 387-410
    3. Yue Hu, Xiao J. Zhang, Xiao T. Yang, Ying Y. Tang, Lin Y. Hu, Dong Zhu
      Pages 411-439
  5. Clinical Aspects of HSP90

    1. Front Matter
      Pages 471-471
    2. Luca Ferrari, Stefan G. D. Rüdiger
      Pages 473-491
    3. Ganapasam Sudhandiran, Divya Thomas, Vadivel Dineshbabu, Soumya Krishnan
      Pages 493-506
    4. Yan Zhao, Yuan-Guo Zhou
      Pages 533-545
    5. João Dias-Ferreira, Fani L. Moreira Neto
      Pages 547-574
    6. Visith Thongboonkerd
      Pages 575-589
  6. Back Matter
    Pages 605-607

About this book


The book Heat Shock Protein 90 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP90. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, previously unknown signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding Oncogenic Aspects of HSP90; Section II, focuses on Bimolecular Aspects of HSP90; Section III, emphasizes and HSP90 in Natural Products Development and Section IV; give the most up to date reviews on Clinical Aspects of HSP90.  

Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Natural Products, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.


Immunological and inflammatory responses Physiological responses Extracellular heat shock protein Chaperone Cytokine

Editors and affiliations

  • Alexzander A. A. Asea
    • 1
  • Punit Kaur
    • 2
  1. 1.Department of Medicine and Director, Precision Therapeutics Proteogenomics Diagnostic Center, Eleanor N. Dana Cancer CenterUniversity of Toledo, College of Medicine and Life SciencesToledoUSA
  2. 2.Department of Experimental Radiation OncologyMD Anderson Cancer CenterHoustonUSA

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