Atherosclerosis Pathogenesis and Microvascular Dysfunction

  • Axel Haverich
  • Erin Colleen Boyle

Table of contents

  1. Front Matter
    Pages i-x
  2. Axel Haverich, Erin Colleen Boyle
    Pages 1-7
  3. Axel Haverich, Erin Colleen Boyle
    Pages 9-45
  4. Axel Haverich, Erin Colleen Boyle
    Pages 47-54
  5. Axel Haverich, Erin Colleen Boyle
    Pages 115-127
  6. Back Matter
    Pages 129-130

About this book


This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned.

Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.


Vasa Vasorum Atherosclerosis Microcirculation Cardiovascular Disease Neoangiogenesis Microthrombosis

Authors and affiliations

  • Axel Haverich
    • 1
  • Erin Colleen Boyle
    • 2
  1. 1.Hannover Medical SchoolHannoverGermany
  2. 2.Hannover Medical SchoolHannoverGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-030-20244-6
  • Online ISBN 978-3-030-20245-3
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology