Periodic and Non-Periodic Fevers

  • Rolando Cimaz

Part of the Rare Diseases of the Immune System book series (RDIS)

Table of contents

  1. Front Matter
    Pages i-x
  2. Marco Gattorno
    Pages 1-20
  3. Estíbaliz Iglesias, Antoni Noguera-Julian, Laia Alsina, Jordi Antón
    Pages 21-26
  4. Rakesh Kumar Pilania, Surjit Singh
    Pages 45-63
  5. María Martha Katsicas, Ricardo A. G. Russo
    Pages 65-91
  6. Stéphane Mitrovic, Eugen Feist, Bruno Fautrel
    Pages 93-132
  7. Antonio Brucato, Anna Valenti, Silvia Maestroni
    Pages 133-146
  8. Andrea Taddio, Serena Pastore
    Pages 147-160
  9. Erdal Sag, Yelda Bilginer, Seza Ozen
    Pages 161-175
  10. Skirmante Rusoniene, Vaidotas Urbonas, Tadej Avcin
    Pages 177-213
  11. Dale M. Kobrin, David C. Fajgenbaum
    Pages 215-228
  12. Brigitte Bader-Meunier
    Pages 229-234
  13. Charalampia Papadopoulou, Helen J. Lachmann
    Pages 235-245
  14. Cécile Frachette, Rolando Cimaz, Alexandre Belot
    Pages 247-256
  15. Serife Gulmus, Roberta Berard, Erkan Demirkaya
    Pages 257-272
  16. Back Matter
    Pages 281-283

About this book


This book, written by very well-known opinion leaders in the field, covers all aspects of periodic and non –periodic fevers, and related disorders. The expression refers to several different auto-inflammatory diseases, showing similar symptoms–the primary symptom being a recurrent fever for an infectious cause cannot be found.  The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications in both pediatric and adult patients. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area.

The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Periodic and Non-Periodic Fevers will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these disease.


Autoinflammatory sindrome Recurrent fevers Monogenic disorders Innate immunity Genetic disorders Amyloidosis Proteasome related disorders Interferonopathies

Editors and affiliations

  • Rolando Cimaz
    • 1
  1. 1.Department of Clinical Sciences and Community HealthUniversity of MilanoMilanoItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-030-19054-5
  • Online ISBN 978-3-030-19055-2
  • Series Print ISSN 2282-6505
  • Series Online ISSN 2283-6403
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology