© 2020

Surgery of the Cranio-Vertebral Junction

  • Enrico Tessitore
  • Amir R. Dehdashti
  • Claudio Schonauer
  • Claudius Thomé

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Elena d’Avella, Luigi Maria Cavallo, Matteo De Notaris, Jose Pineda, Alberto Di Somma, Paolo Cappabianca et al.
      Pages 3-42
    3. Mario Muto, Francesco Giurazza, Carlo Augusto Mallio, Gianluigi Guarnieri, Roberto Izzo
      Pages 61-85
    4. Francesco Signorelli, Massimiliano Visocchi
      Pages 87-94
    5. Ibrahim Obeid, Derek T. Cawley
      Pages 95-108
  3. Perioperative Considerations

    1. Front Matter
      Pages 109-109
    2. Claudio Schonauer, Enrico Tessitore
      Pages 111-116
    3. Dominic J. Nardi, Shamik Chakraborty, Amir R. Dehdashti
      Pages 117-124
    4. Granit Molliqaj, Matthias Robin, Christoph Czarnetzki, Marie-Josée Daly, Americo Agostinho, Enrico Tessitore
      Pages 125-138
  4. Surgical Techniques

    1. Front Matter
      Pages 157-157
    2. David Choi
      Pages 159-169
    3. Felice Esposito, Fabio Cacciola, Domenico Solari, Rosa Maria Gerardi, Filippo Flavio Angileri, Oreste de Divitiis et al.
      Pages 171-186
    4. Andrea Brunori, Daniele Marruzzo, Valentina Russo, Alberto Delitala
      Pages 187-196
    5. Joseph A. Osorio, Markus Schomacher, Christopher P. Ames
      Pages 197-206
    6. Yann Philippe Charles
      Pages 207-217
    7. Naveed Kamal, Renuka K. Reddy, Takanori Fukushima, James K. Liu
      Pages 219-235
    8. Kentaro Watanabe, Moujahed Labidi, Shunya Hanakita, Bernard George, Sébastien Froelich
      Pages 237-260

About this book


This book provides a unique tool for approaching cranio-vertebral junction (CVJ) surgery. Following a brief introduction to the relevant anatomy and biomechanics of CVJ, it explores the field of cranio-vertebral junction lesions and their management. Furthermore, individual chapters cover endovascular surgery, endoscopic skull base techniques, navigation and robotics, ensuring that surgeons stay up-to-date. A chapter addressing the consequences of CVJ surgery with regard to sagittal balance is of particular importance. The book is structured according both to the type of lesion involving the CVJ (tumor, trauma), and to the type of surgical approach (anterior, posterior). Further, it reflects innovative treatment modalities that have improved patient safety and efficacy rates for surgery involving the CVJ, and covers both open and minimally invasive surgical methods, enabling surgeons to hone their skills in both areas. 


tumors aneurysms trauma Chiari malformation infections instability sagittal balance fusion complications

Editors and affiliations

  • Enrico Tessitore
    • 1
  • Amir R. Dehdashti
    • 2
  • Claudio Schonauer
    • 3
  • Claudius Thomé
    • 4
  1. 1.Neurosurgical UnitGeneva University HospitalsGenevaSwitzerland
  2. 2.Department of NeurosurgeryNorth Shore University HospitalsManhassetUSA
  3. 3.Neurosurgical UnitASL Napoli 2 NordNaplesItaly
  4. 4.Department of NeurosurgeryInnsbruck University HospitalsInnsbruckAustria

About the editors

Enrico Tessitore, MD, PD, is the Deputy Chairman of the Neurosurgical Unit at the Geneva University Hospitals in Switzerland, and he is Privat Docent at the Medical School of the University of Geneva. He is Co-Director of the Cancer Center of Geneva University Hospital and responsible for bone metastasis Tumor Board. He’s been trained in Naples (Italy) and then moved to Geneva, where he completed the residency program. Dr. Tessitore has significant clinical expertise in performing spinal surgical procedures for degenerative diseases, tumors, deformity, infection and trauma.

Dr. Tessitore has published over 80 papers and has given more than 120 lectures at different national and international meetings on topics relevant to spine diseases.

He is Member of the Educational Committee (EduCom) of the Eurospine society. He affiliated at the following societies: Eurospine, EANS, EANS spine section, AO Spine, Italian Neurosurgical Society (SINCH), SINCH Spine Section, Swiss Neurosurgical Society, Swiss Spine Society, and he is also advisory board member of the Journal of Neurosurgical Sciences and European Spine Journal. His main clinical research areas are the Cranio-vertebral junction surgery, Minimally invasive spine surgery, Robotic spine surgery, Thoracoscopic spine surgery, Spine deformity and spinal tumor surgery. 

Amir R. Dehdashti, MD, FACS, FMH is the Director of Cerebrovascular Neurosurgery Research at North Shore University Hospital and Associate Professor of Neurosurgery at Hofstra Northwell School of Medicine in New York. Dr. Dehdashti completed his neurosurgery training under Professor de Tribolet in Geneva, Switzerland, and is board certified in neurosurgery by both the Swiss Board and the Board of the European Association of Neurosurgical Societies. Dr. Dehdashti completed fellowship training in both cerebrovascular and skull base surgery, including endoscopic skull base surgery, at the Toronto Western Hospital. He is one of the few dually trained cerebrovascular and skull base surgeons in the country with two dedicated and separate fellowships. Dr. Dehdashti has significant clinical expertise in performing complex intracranial surgery including cerebral bypass procedure which is performed only by a handful of expert neurosurgeons in the country. Dr. Dehdashti has published over 100 papers and has given more than 200 lectures at different national and international meetings on topics relevant to cerebrovascular, skull base tumors, pituitary tumors and cranial nerve disorders including trigeminal neuralgia. He has been involved in several retrospective and prospective studies relating to cerebrovascular neurosurgery. Dr. Dehdashti's clinical expertises include cerebrovascular surgery (aneurysm, AVM, brainstem cavernous malformation, Moyamoya disease, cerebral revascularization), carotid endarterectomy, minimally invasive surgery for aneurysms (mini craniotomy), minimally invasive endoscopic skull base surgery (pituitary and skull base tumors), surgery for cranial nerve disorders (trigeminal neuralgia, hemifacial spasm, glossopharyngeal neuralgia), skull base surgery, craniovertebral junction pathologies and acoustic neuroma surgery. His basic science and laboratory research is focused on molecular biology of brain AVMs. He is actively involved in the executive committees of North American Skull Base Society and Cerebrovascular Section of the AANS.  

Claudio Schonauer, MD PhD, is Consultant of the Neurosurgical Unit at the ASLNapoli2 in Naples Italy . Specialist in Neurosurgery since 2000 and PhD in Neurooncology since 2004. He spent different years around Europe in France (Lyon and Paris) and Erlangen (Germany).

In 2015 was Consultant  Neurosurgeon at the  University of Geneva  Suisse.

He was Chairman for Neurosurgery of the Italian Society of Young Surgeons, is SINCH board member since 1998 and from 2010 as Faculty member. Is a Faculty member of AO spine International . His  surgical intersts moves from brain to spine surgery with expertise in ventricular Neuroendoscopy , complex spine and ventricular microsurgery. He has performed about  2000 brain and spine operations as first surgeon. He is present as reviewer in the  editorial board of 7 indexed/impacted journals. Author of 61 published papers and different book chapters in neurosurgical international books. 

Claudius Thome, MD, is Professor and Chairman of the Department of Neurosurgery at the Medical University Innsbruck, Austria.  He is member at of the following societies: American Association of Neurological Surgeons (AANS), AO Spine (Education Officer Europe), Austrian Society of Neurosurgery (ÖGNC, President), Austrian Society of Surgery (ÖGCH, President), Austrian Spine Society (ÖGW, Past President), German Academy of Neurosurgery (GANS, Secretary), German Society of Neurosurgery (DGNC),  German Spine Society (DWG), European Association of Neurosurgical Societies (EANS; Chair-Elect of the Training Committee) and Spine Society of Europe (SSE). The main areas of research are evidence-based and minimal-invasive as well as complex spine surgery incl. regenerative approaches, spinal instrumentation and navigation, cerebrovascular surgery including revascularization, subarachnoid haemorrhage/cerebral vasospasm and neurotrauma incl. neurointensive care and neuromonitoring plus minimal-invasive skull base surgery. 

Bibliographic information

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“The book is aimed at neurosurgeons. It presents both basic concepts and innovative approaches including robotics, navigation, and endovascular and endoscopic techniques. It would probably be of more interest to neurosurgery residents and fellows who are looking for an introduction to this complex neurosurgical territory. … I will highly recommend it to my colleagues and trainees, particularly those who are interested in operating at the junction between the brain and spinal cord and between the skull and vertebral column.” (Konstantin V. Slavin, Doody’s Book Reviews, July 10, 2020)