© 2019

The Role of Bacteria in Urology

  • Dirk Lange
  • Kymora B. Scotland
  • Discusses the signs and symptoms of urosepsis to help the reader recognise and identify patients suffering from it

  • Feature diagrams and tables illustrating different pathogenic mechanisms used by common uropathogens to give a better understanding of how bacteria infect the urinary tract

  • Covers basic bacterial resistance mechanisms in a concise manner to gives readers an understanding of common bacterial resistance


Table of contents

  1. Front Matter
    Pages i-viii
  2. Justin Y. H. Chan, Kymora B. Scotland, Dirk Lange
    Pages 9-22
  3. Kaylen O’Rourke, Peter A. Cadieux
    Pages 23-39
  4. Samir Bidnur, Kymora B. Scotland
    Pages 41-50
  5. Benjamin Shiff, Ryan Flannigan
    Pages 51-60
  6. Erika J. Espinosa-Ortiz, Robin Gerlach
    Pages 61-70
  7. Tim Large, Amy E. Krambeck
    Pages 71-78
  8. Liam Brennan, Kaitlin F. Al, Jennifer Bjazevic, Hassan Razvi, Jeremy P. Burton
    Pages 79-93
  9. Roland Seiler, Peter C. Black
    Pages 103-118
  10. Whitney Smith, Alana Murphy
    Pages 119-124
  11. Claudia Chavez-Munoz, Bhavish Kowlessur, Alan So
    Pages 125-135
  12. Louisa Ho, Simran Parmar, Kymora B. Scotland
    Pages 137-146
  13. Victor Wong, Dirk Lange
    Pages 147-157
  14. Colin Lundeen, Kymora B. Scotland
    Pages 159-168
  15. Ryan Dornbier, Petar Bajic, Andrew Schwaderer, Alan J. Wolfe
    Pages 169-178
  16. Back Matter
    Pages 187-193

About this book


This updated volume provides a concise guide to the pathogenic, therapeutic, and preventative roles of bacteria in urology. New chapters discussing the involvement of the microbiome in the areas of recurrent kidney stone disease, female urology, and prostate cancer are included. The treatment of urosepsis, stone management, genitourinary malignancy, stone sequencing, and the role of microbiome and virome in urology are also covered.

The Role of Bacteria in Urology is relevant to both clinicians and scientists interested in the infection of the genitourinary system.


Bacterial Pathogenesis Bacterial Resistance Mechanisms Infection Urinary Tract Infection Urologic Disease Urosepsis Genitourinary system Microbiome and virome Stone management Kidney stone disease

Editors and affiliations

  • Dirk Lange
    • 1
  • Kymora B. Scotland
    • 2
  1. 1.University of British Columbia, The Stone Centre at Vancouver General Hospital, Jack Bell Research CentreVancouverCanada
  2. 2.University of British Columbia, The Stone Centre at Vancouver General Hospital, Jack Bell Research CentreVancouverCanada

About the editors

Dr. Dirk Lange is a microbiologist who earned his Ph.D. in Microbiology and Immunology from the University of Western Ontario (London, Ontario) on understanding the role of the capsular polysaccharide in the pathogenesis of Campylobacter jejuni. Dr. Lange completed his post-doctoral fellowship at The Stone Centre at VGH with Dr. Ben Chew, where he contributed significantly to the area of urinary biomaterial design, providing a basic science perspective to understanding ureteral stent related morbidity. Due to his significant contributions to the research program at the Stone Centre, Dr. Lange was recruited to the Department of Urologic Sciences as an Assistant Professor in 2011, and is also the Director of Basic Science Research at the Stone Centre. Dr. Lange continues to run a research program aimed at studying the role of bacteria in urology, specifically the development of novel therapies for recurrent kidney stone disease based on the intestinal microbiome as well as the development of novel technologies to prevent indwelling device associated urinary tract infections.

Dr. Kymora Scotland is the endourology fellow at the Stone Centre of the Department of Urologic Sciences at the University of British Columbia. Dr. Scotland is a graduate of the Tri-Institutional Cornell/Rockefeller/Sloan Kettering MD-PhD Program with a background in genitourinary pharmacology and molecular biology.  She then completed her urology residency at Thomas Jefferson University Hospital where her clinical research concentrated on the endourologic management of kidney stones and upper tract urothelial cancer. Her postgraduate work at the Stone Centre has investigated ureteral stent associated urinary tract infections by further elucidating the mechanism of biofilm formation on stents.  Future research endeavors will continue to center on translational work that has direct relevance to her patients. Dr. Scotland will explore the effect of the urinary microbiome on genitourinary disease..

Bibliographic information

  • Book Title The Role of Bacteria in Urology
  • Editors Dirk Lange
    Kymora B. Scotland
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-030-17541-2
  • Softcover ISBN 978-3-030-17544-3
  • eBook ISBN 978-3-030-17542-9
  • Edition Number 2
  • Number of Pages VIII, 193
  • Number of Illustrations 4 b/w illustrations, 12 illustrations in colour
  • Topics Urology
    Infectious Diseases
  • Buy this book on publisher's site
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