© 2019

Stem Cells Heterogeneity in Cancer

  • Alexander Birbrair
  • International expertise and experience in one volume

  • Comprehensive; provides background and current information and applications

  • Cogent organization, disease by disease, allowing quick access to specific information


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1139)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Daniel V. Brown, Stanley S. Stylli, Andrew H. Kaye, Theo Mantamadiotis
    Pages 1-21
  3. Xu Qian, Xiaobo Nie, Barbara Wollenberg, Holger Sudhoff, Andreas M. Kaufmann, Andreas E. Albers
    Pages 23-40
  4. D. Prabavathy, Niveditha Ramadoss
    Pages 41-57
  5. Caecilia H. C. Sukowati
    Pages 59-81
  6. Bárbara Sousa, Ana Sofia Ribeiro, Joana Paredes
    Pages 83-103
  7. Elisabeth A. Seftor, Naira V. Margaryan, Richard E. B. Seftor, Mary J. C. Hendrix
    Pages 105-114
  8. Akihiro Hirata, Yuichiro Hatano, Masayuki Niwa, Akira Hara, Hiroyuki Tomita
    Pages 115-126
  9. Michaela Kripnerova, Hamendra Singh Parmar, Martin Pesta, Michaela Kohoutova, Jitka Kuncova, Karel Drbal et al.
    Pages 127-151
  10. Theodoros Karantanos, Richard J. Jones
    Pages 153-169
  11. Kristina Schiavone, Delphine Garnier, Marie-Francoise Heymann, Dominique Heymann
    Pages 187-200
  12. Jiri Hatina, Maximilian Boesch, Sieghart Sopper, Michaela Kripnerova, Dominik Wolf, Daniel Reimer et al.
    Pages 201-221
  13. Back Matter
    Pages 223-228

About this book


This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ.

Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity – Novel Concepts, and Stem Cells Heterogeneity in Different Organs, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians. 


stem cells heterogeneity cell surface marker stem cell subtypes cell cycle status cancer stem cells

Editors and affiliations

  • Alexander Birbrair
    • 1
  1. 1.Department of Pathology, Federal University of Minas GeraisDepartment of Radiology, Columbia University Medical Center, New York, NY, USABelo Horizonte, MGBrazil

About the editors

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC).

Bibliographic information

Industry Sectors