Flammer Syndrome

From Phenotype to Associated Pathologies, Prediction, Prevention and Personalisation

  • Olga Golubnitschaja

Part of the Advances in Predictive, Preventive and Personalised Medicine book series (APPPM, volume 11)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Josef Flammer, Katarzyna Konieczka
    Pages 9-17
  3. Olga Golubnitschaja, Detlef E. Dietrich, Dieter Felbel, Vincenzo Costigliola
    Pages 19-28
  4. Bernhard A. Sabel, Jiaqi Wang, Lizbeth Cárdenas-Morales, Muneeb Faiq, Christine Heim, Olga Golubnitschaja
    Pages 29-77
  5. Analtolij Kunin, Jiri Polivka Jr, Natalia Moiseeva, Olga Golubnitschaja
    Pages 105-123
  6. Vadym Goncharenko, Rostyslav Bubnov, Jiri Polivka, Pavol Zubor, Kamil Biringer, Tibor Bielik et al.
    Pages 125-134
  7. Kneginja Richter, Lukas Peter, Lence Miloseva, Thomas Hillemacher, Günter Niklewski, Olga Golubnitschaja
    Pages 135-143
  8. Jiri Polivka Jr, Jiri Polivka, Martin Pesta, Vladimir Rohan, Libuse Celedova, Rostislav Cevela et al.
    Pages 165-181
  9. Babak Baban, Olga Golubnitschaja
    Pages 183-192
  10. Olga Golubnitschaja, Pavol Zubor, Jiri Polivka Jr., Ivica Smokovski, Alexandra Gondova, Petra Kasajova et al.
    Pages 205-241
  11. Rostyslav Bubnov, Jiri Polivka Jr., Pavol Zubor, Katarzyna Konieczka, Olga Golubnitschaja
    Pages 243-263
  12. Kristina Biskupska Bodova, Zuzana Laucekova, Olga Golubnitschaja, Pavol Zubor
    Pages 277-285
  13. Wei Wang, Xuerui Tan
    Pages 287-315
  14. Back Matter
    Pages 371-376

About this book


Unmet healthcare needs of young populations and individuals in suboptimal health conditions are the key issue of currently observed epidemics of non-communicable disorders. Moreover, an unprecedented decrease in the average age of onset of these disorders is recorded. The majority of non-communicable disorders carry a chronic character by progressing over a couple of years from a reversible suboptimal health condition to irreversible pathology with collateral complications. The time-frame between both conditions is the operational area for predictive diagnosis and identification of persons at risk by innovative screening programmes followed by the most cost-effective personalised treatment possible, namely primary prevention tailored to the person.

The book propagates the paradigm change from delayed, costly but frequently ineffective medical services to the holistic approach by predictive, preventive and personalised medicine clearly demonstrating multifaceted benefits to the individual, healthcare sector and society as a whole.

The book is focused on the needs of

  • young people: teenagers, adolescents and young adults;
  • regardless of the age, individuals in suboptimal health conditions, who are interested in remaining healthy by optimising their modifiable risk factors – both endogenous and exogenous ones;
  • several patient cohorts demonstrating similar phenotype of Flammer syndrome.

The book is based on the multi-professional expertise, scientific excellence and practical experiences of the world-acknowledged experts in Flammer syndrome, predictive diagnostics, targeted prevention and personalised medicine, amongst others. The topic of this book is particularly relevant to general practitioners, experts in non-communicable diseases, phenotyping, genotyping, multilevel diagnostics, targeted prevention, personalised medicine, as well as the readers interested in advancing their health literacy.


Flammer Syndrome Primary vascular dysregulation Predictive Diagnosis Targeted prevention Personalized Medicine

Editors and affiliations

  • Olga Golubnitschaja
    • 1
  1. 1.Department of RadiologyFriedrich-Wilhelms-University in BonnBonnGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-030-13549-2
  • Online ISBN 978-3-030-13550-8
  • Series Print ISSN 2211-3495
  • Series Online ISSN 2211-3509
  • Buy this book on publisher's site
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