Cell-Based Therapy for Degenerative Retinal Disease

  • Marco A. Zarbin
  • Mandeep S. Singh
  • Ricardo P. Casaroli-Marano

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Karl A. Z. Hudspith, Gibert Xue, Mandeep S. Singh
    Pages 11-28
  3. Ricardo P. Casaroli-Marano, Núria Nieto-Nicolau, Raquel A. Martínez-García de la Torre
    Pages 53-80
  4. Brian Fury, Henry Klassen, Gerhard Bauer
    Pages 81-95
  5. Marta Stevanovic, Debbie Mitra, Dennis O. Clegg, Mark S. Humayun
    Pages 109-140
  6. Harpal Sandhu, Janelle M. F. Adeniran, Henry J. Kaplan
    Pages 141-156
  7. Odysseas Georgiadis, Peter J. Coffey, Lyndon da Cruz
    Pages 167-192
  8. Young Ju Lew, Jacque L. Duncan
    Pages 193-216
  9. Francesco Sottile, Martina Pesaresi, Giacoma Simonte, Maria Pia Cosma
    Pages 217-244
  10. Kanza Aziz, Marco A. Zarbin, Mandeep S. Singh
    Pages 245-265
  11. Mandeep S. Singh, Marco A. Zarbin
    Pages 267-271
  12. Back Matter
    Pages 273-280

About this book


This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology. 


retinal pigment epithelium cns cell therapy stem cells reprogramming cells neural progenitor cells

Editors and affiliations

  • Marco A. Zarbin
    • 1
  • Mandeep S. Singh
    • 2
  • Ricardo P. Casaroli-Marano
    • 3
  1. 1.Institute of Ophthalmology and Visual ScienceRutgers New Jersey Medical SchoolNewarkUSA
  2. 2.Wilmer Eye InstituteJohns Hopkins University, School of MedicineBaltimoreUSA
  3. 3.Department of Surgery School of Medicine & Hospital Clinic of BarcelonaUniversity of BarcelonaBarcelonaSpain

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