© 2019


Genome-Scale Analysis of Ancient DNA

  • Charlotte Lindqvist
  • Om P. Rajora

Part of the Population Genomics book series (POGE)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Concepts, Technical Advances and Challenges

    1. Front Matter
      Pages 1-1
    2. Oliver Smith, M. Thomas P. Gilbert
      Pages 53-74
    3. Kristian Hanghøj, Ludovic Orlando
      Pages 75-111
  3. Paleogenomics Case Studies: From Ancient Pathogens to Primates

    1. Front Matter
      Pages 113-113
    2. Stephanie Marciniak, Hendrik N. Poinar
      Pages 115-138
    3. Kyriakos Tsangaras, Alex D. Greenwood
      Pages 139-162
    4. Laura Parducci, Kevin Nota, Jamie Wood
      Pages 163-187
    5. Robin G. Allaby, Oliver Smith, Logan Kistler
      Pages 189-203
    6. Freek T. Bakker
      Pages 205-224
    7. Evan K. Irving-Pease, Hannah Ryan, Alexandra Jamieson, Evangelos A. Dimopoulos, Greger Larson, Laurent A. F. Frantz
      Pages 225-272
    8. Olaf Thalmann, Angela R. Perri
      Pages 273-306
    9. Ludovic Orlando
      Pages 325-351
    10. Krishna R. Veeramah
      Pages 353-373
    11. Skyler D. Resendez, Justin R. Bradley, Duo Xu, Omer Gokcumen
      Pages 375-391
    12. Johanna von Seth, Jonas Niemann, Love Dalén
      Pages 393-418
  4. Back Matter
    Pages 419-427

About this book


Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches.  Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.


Paleogenomics Adaptation Evolution Extinction Genomics Ice Ages

Editors and affiliations

  • Charlotte Lindqvist
    • 1
  • Om P. Rajora
    • 2
  1. 1.Department of Biological SciencesUniversity at Buffalo (SUNY)BuffaloUSA
  2. 2.Faculty of Forestry and Environmental ManagementUniversity of New BrunswickFrederictonCanada

About the editors

Dr. Charlotte Lindqvist
Associate Professor
University at Buffalo (SUNY)
Department of Biological Sciences
Buffalo, NY

Dr. Om P. Rajora
University of New Brunswick
Fredericton, NB E3C 5A3

Bibliographic information


“This book is intended for a variety of readers, including upper-level undergraduate and graduate students, professionals, and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers. This well-written volume is for well-read undergraduate students, and is definitely a good read for graduate students and professionals.” (Lorin R. King, The Quarterly Review of Biology, Vol. 95 (4), December, 2020)