Table of contents

  1. Front Matter
    Pages i-xi
  2. Inflammatory Signaling Pathways

    1. Front Matter
      Pages 1-1
    2. Burcu Hasdemir, Dina Shakran, Sreenivasan Paruthiyil, Aditi Bhargava
      Pages 23-40
    3. Udayakumar Prithika, Krishnaswamy Balamurugan
      Pages 91-100
    4. Fabiano T. Amorim, Micah N. Zuhl
      Pages 101-119
    5. Anil K. Chauhan
      Pages 121-137
    6. Lakshmikanthan Panneerselvam, Azhwar Raghunath, Kiruthika Sundarraj, Ekambaram Perumal
      Pages 139-159
    7. Wei Lei, David Duron, Carrie Stine, John M. Streicher
      Pages 161-182
  3. Oncology Signaling Pathways

    1. Front Matter
      Pages 231-231
    2. Vijay P. Kale, Sangita Phadtare, Shantu G. Amin, Manoj K. Pandey
      Pages 233-251
    3. Liang Wenjin, Li Zeming, Liao Yong, Wang Yan, Tang Bo
      Pages 273-287
    4. Vadim Lincoln, Xin Tang, Mei Chen, Wei Li
      Pages 289-315
    5. Aaron S. Bernstein, Daniel G. Jay
      Pages 329-344
    6. Laura E. Knighton, Andrew W. Truman
      Pages 345-358
    7. Suman Chatterjee, Timothy F. Burns
      Pages 359-395
  4. Neurological Signaling Pathways

    1. Front Matter
      Pages 431-431
    2. Candelaria Merino-Jiménez, César García-Cruz, Jorge Aragón, Lourdes Siqueiros-Márquez, Cecilia Montañez
      Pages 433-458
  5. Back Matter
    Pages 479-482

About this book


This edited volume offers an insightful overview of contemporary research on signaling pathways. These signaling processes are the comprehensive mechanisms by which all cellular organisms communicate internally and externally with their microenvironment. The volume is focused on heat shock proteins (HSP), which are uniquely involved in a number of critical signaling pathways.

Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. The knowledge gained from better understanding these mechanisms can help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders.

Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.


HSP expression Cell death Cancer Inflammatory diseases Neurological disorders Targeted treatment therapies

Editors and affiliations

  • Alexzander A. A. Asea
    • 1
  • Punit Kaur
    • 2
  1. 1.Professor, Department of Medicine and Director, Precision Therapeutics Proteogenomics Diagnostic Center Eleanor N. Dana Cancer CenterUniversity of Toledo College of Medicine and Life SciencesToledoUSA
  2. 2.Department of Experimental Radiation OncologyMD Anderson Cancer CenterHoustonUSA

Bibliographic information

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