Table of contents

  1. Front Matter
    Pages i-xv
  2. Marcus J. Schultz, Martin W. Dünser, Arjen M. Dondorp, Neill K. J. Adhikari, Shivakumar Iyer, Arthur Kwizera et al.
    Pages 1-24 Open Access
  3. Alfred Papali, Neill K. J. Adhikari, Janet V. Diaz, Arjen M. Dondorp, Martin W. Dünser, Shevin T. Jacob et al.
    Pages 31-68 Open Access
  4. Arthur Kwizera, Neill K. J. Adhikari, Derek C. Angus, Arjen M. Dondorp, Martin W. Dünser, Emir Festic et al.
    Pages 69-84 Open Access
  5. Mervyn Mer, Marcus J. Schultz, Neill K. J. Adhikari, Arthur Kwizera, Sanjib Mohanty, Arjen M. Dondorp et al.
    Pages 85-129 Open Access
  6. Ary Serpa Neto, Marcus J. Schultz, Emir Festic, Neill K. J. Adhikari, Arjen M. Dondorp, Rajyabardhan Pattnaik et al.
    Pages 131-149 Open Access
  7. David Misango, Rajyabardhan Pattnaik, Tim Baker, Martin W. Dünser, Arjen M. Dondorp, Marcus J. Schultz
    Pages 151-162 Open Access
  8. C. Louise Thwaites, Ganbold Lundeg, Arjen M. Dondorp, Neill K. J. Adhikari, Jane Nakibuuka, Randeep Jawa et al.
    Pages 163-184 Open Access
  9. Arjen M. Dondorp, Mai Nguyen Thi Hoang, Mervyn Mer, Martin W. Dünser, Sanjib Mohanty, Jane Nakibuuka et al.
    Pages 185-195 Open Access
  10. Ndidiamaka Musa, Srinivas Murthy, Niranjan Kissoon, Rakesh Lodha, Suchitra Ranjit
    Pages 197-216 Open Access

About this book


This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings.

More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion. 


Open Access Recommendations Resource-limited settings Low-income countries Middle-income countries Evidence-based medicine

Editors and affiliations

  • Arjen M. Dondorp
    • 1
  • Martin W. Dünser
    • 2
  • Marcus J. Schultz
    • 3
  1. 1.Mahidol-Oxford Research Unit (MORU), Faculty of Tropical MedicineMahidol UniversityBangkokThailand
  2. 2.Department of Anesthesiology and Intensive Care MedicineKepler University Hospital, Johannes Kepler University of LinzLinzAustria
  3. 3.Mahidol-Oxford Research Unit (MORU), Faculty of Tropical MedicineMahidol UniversityBangkokThailand

Bibliographic information

  • DOI
  • Copyright Information The Editor(s) (if applicable) and The Author(s) 2019
  • License CC BY
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-030-03142-8
  • Online ISBN 978-3-030-03143-5
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology