Advances in Heart Valve Biomechanics

Valvular Physiology, Mechanobiology, and Bioengineering

  • Michael S. Sacks
  • Jun Liao

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Native Heart Valve Function

    1. Front Matter
      Pages 1-1
    2. Alex Khang, Rachel M. Buchanan, Salma Ayoub, Bruno V. Rego, Chung-Hao Lee, Michael S. Sacks
      Pages 3-36
    3. James N. Warnock
      Pages 37-58
    4. Varun K. Krishnamurthy, K. Jane Grande-Allen
      Pages 59-79
    5. William D. Meador, Mrudang Mathur, Manuel K. Rausch
      Pages 105-114
    6. Morten O. Jensen, Andrew W. Siefert, Ikechukwu Okafor, Ajit P. Yoganathan
      Pages 115-149
  3. Heart Valve Disease and Treatment

    1. Front Matter
      Pages 151-151
    2. Payal Vyas, Joshua D. Hutcheson, Elena Aikawa
      Pages 153-179
    3. Bruno V. Rego, Sarah M. Wells, Chung-Hao Lee, Michael S. Sacks
      Pages 181-206
    4. Lindsey J. Anstine, Anthony S. Baker, Joy Lincoln
      Pages 207-239
    5. Ishita Tandon, Ngoc Thien Lam, Kartik Balachandran
      Pages 241-262
    6. Jay M. Reimer, Robert T. Tranquillo
      Pages 263-288
    7. Katherine M. Copeland, Bo Wang, Xiaodan Shi, Dan T. Simionescu, Yi Hong, Pietro Bajona et al.
      Pages 289-317
    8. Kristin Comella, Sharan Ramaswamy
      Pages 319-335
    9. Naren Vyavahare, Hobey Tam
      Pages 337-382
  4. Computational Approaches for Heart Valve Function

    1. Front Matter
      Pages 383-383
    2. Ahmed A. Bakhaty, Ali Madani, Mohammad R. K. Mofrad
      Pages 385-411
    3. T. Ristori, A. J. van Kelle, F. P. T. Baaijens, S. Loerakker
      Pages 413-446
    4. Rana Zakerzadeh, Michael C. H. Wu, Will Zhang, Ming-Chen Hsu, Michael S. Sacks
      Pages 447-469
    5. Amir H. Khalighi, Bruno V. Rego, Andrew Drach, Robert C. Gorman, Joseph H. Gorman, Michael S. Sacks
      Pages 471-487

About this book


This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.


GAGs in heart valve biomechanics automated heart valve bioreactors bending force in heart valve development biomechanics in mitral valve repairing biomechanics of myxoid mitral valves biomechanics of transcatheter heart valves biomechanics tissue engineered heart valves cardiac biomaterials computational modeling for the mitral heart valve computational modeling of heart valves decellularized heart valve scaffolds geometrical symmetry in bioprosthetic heart valve heart valve 3D printing heart valve calcification heart valve leaflets heart valve mechanotransduction heart valve tissue engineering mechanobiology of heart valve endothelial cells pregnancy-induced remodeling in heart valves viscoelasticity of heart valve tissues

Editors and affiliations

  • Michael S. Sacks
    • 1
  • Jun Liao
    • 2
  1. 1.The Oden Institute and the Department of Biomedical EngineeringThe University of Texas at AustinAustinUSA
  2. 2.The Department of BioengineeringThe University of Texas at ArlingtonArlingtonUSA

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