Pharmaceutical Biotechnology

Fundamentals and Applications

  • Daan J. A. Crommelin
  • Robert D. Sindelar
  • Bernd Meibohm

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Wim Jiskoot, Daan J. A. Crommelin
    Pages 19-32
  3. Atanas Koulov
    Pages 33-56
  4. Alfred Luitjens, Emile van Corven
    Pages 57-82
  5. Daan J. A. Crommelin, Andrea Hawe, Wim Jiskoot
    Pages 83-103
  6. Wim Jiskoot, Theo Rispens, Grzegorz Kijanka
    Pages 139-150
  7. Rong Deng, C. Andrew Boswell, Wendy S. Putnam, Meina T. Tang, Amit Garg, Chunze Li et al.
    Pages 151-190
  8. Amit S. Patel, Kartick P. Shirur
    Pages 253-263
  9. Vinod P. Shah, Daan J. A. Crommelin
    Pages 265-274
  10. Wim Jiskoot, Gideon F. A. Kersten, Enrico Mastrobattista, Bram Slütter
    Pages 281-304
  11. Raymond M. Schiffelers, Erik Oude Blenke, Enrico Mastrobattista
    Pages 305-322
  12. Hao Wu, Amit Kumar Chaudhary, Ram I. Mahato
    Pages 323-355
  13. John M. Beals, Michael R. DeFelippis, Chad D. Paavola, David P. Allen, Ashish Garg, D. Bruce Baldwin
    Pages 403-427
  14. Tom Sam, Renato de Leeuw
    Pages 429-435
  15. Le N. Dao, Barbara Lippe, Michael Laird, Ingrid Beierle
    Pages 437-449
  16. Koen Mertens, Alexander B. Meijer
    Pages 451-470
  17. Robert A. Lazarus, Jeffrey S. Wagener†
    Pages 471-488
  18. Jürgen Barth
    Pages 489-519
  19. Juan Jose Pérez-Ruixo
    Pages 521-535
  20. Nicole A. Pilch, Holly B. Meadows, Rita R. Alloway
    Pages 537-555
  21. Honghui Zhou, Yan Xu, Amarnath Sharma
    Pages 557-617
  22. Jean-Charles Ryff, Sidney Pestka
    Pages 619-643
  23. Back Matter
    Pages 645-653

About this book


This introductory text explains both the basic science and the applications of biotechnology derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students,
and for those who did not receive formal training in this field. Pharmaceutical Biotechnology: Fundamentals and Applications, Fifth Edition completely updates the previous edition, and includes additional coverage on newer approaches such as oligonucleotides, mi/siRNA, gene therapy and advanced therapeutics.

Daan J.A. Crommelin is Professor Emeritus Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences at Utrecht University, Utrecht, The Netherlands and Adjunct Professor in the Department of Pharmaceutics and Pharmaceutical Chemistry at the University of Utah, Salt Lake City, UT, USA

Robert D. Sindelar is Professor and former Dean Faculty of Pharmaceutical Sciences and The Centre for Health Evaluation & Outcomes Sciences (CHEOS), The University of British Columbia (UBC), Vancouver, BC, Canada and President of the Global Drug Commercialization Centre (GDCC)-China and Vice-President GDCC-worldwide, Chengdu, China

Bernd Meibohm is Professor of Pharmaceutical Sciences and Associate Dean for Research and Graduate Programs at the University of Tennessee Health Science Center, College of Pharmacy, Memphis, TN, USA


Stem cell Enzyme Replacement Therapy recombinant proteins molecular biotechnology pharmacokinetics and Pharmacodymanics proteins and peptides immunogenecity monoclonal antibodies genomics personalized medicine biosimilars vaccines gene therapy FSH

Editors and affiliations

  • Daan J. A. Crommelin
    • 1
  • Robert D. Sindelar
    • 2
  • Bernd Meibohm
    • 3
  1. 1.Utrecht UniversityUtrechtThe Netherlands
  2. 2.Faculty of Pharmaceutical Sciences and The Centre for Health Evaluation & Outcomes Sciences (CHEOS)The University of British Columbia (UBC)VancouverCanada
  3. 3.College of PharmacyUniversity of Tennessee, Health Science CenterMemphisUSA

Bibliographic information

Industry Sectors
Health & Hospitals
Consumer Packaged Goods