© 2018

Natural Products as Source of Molecules with Therapeutic Potential

Research & Development, Challenges and Perspectives

  • Valdir Cechinel Filho


  • Presents chapters written by respected international experts from different research fields

  • Covers all aspects of research on drugs from natural products

  • Explains strategic methods to obtain medicinal agents

  • Provides illustrative and current practice examples


Table of contents

  1. Front Matter
    Pages i-xii
  2. Rivaldo Niero, Valdir Cechinel Filho, Rosendo Augusto Yunes
    Pages 1-33
  3. Giovanna Simonetti, Alessio Valletta, Olga Kolesova, Gabriella Pasqua
    Pages 35-71
  4. Luiz Carlos Klein-Júnior, Johan Viaene, Amorn Slosse, Yvan Vander Heyden
    Pages 73-109
  5. Adriana Campos, Elisa Brasili, Camile Cecconi Cechinel-Zanchett, Valdir Cechinel Filho
    Pages 111-157
  6. Liliana V. Muschietti, Jerónimo L. Ulloa, Flavia DC. Redko
    Pages 159-208
  7. Wiesław Szeja, Grzegorz Grynkiewicz
    Pages 233-307
  8. Benjamin Kirchweger, Judith M. Rollinger
    Pages 333-364
  9. Ashik Mosaddik, Vijaya Ravinayagam, Silviya Elaanthikkal, Hatem Fessi, Waisudin Badri, Abdelhamid Elaissari
    Pages 391-463
  10. Gloria Ivonne Hernández-Bolio, Luis Manuel Peña-Rodríguez
    Pages 465-494
  11. Dâmaris Silveira, Jose M. Prieto, Marcela M. Freitas, Andre L. D. A. Mazzari
    Pages 495-515
  12. Back Matter
    Pages 517-531

About this book


This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field. It also provides a detailed overview of the strategies used to research and develop these drugs.

Respected experts explore issues involved in the production chain and when looking for new medicinal agents, including aspects such as therapeutic potential, functional foods, ethnopharmacology, metabolomics, virtual screening and regulatory scenarios.

Further, the book describes strategic methods of isolation and characterization of active principles, biological assays, biotechnology of plants, synthesis, clinical trials and the use of tools to identity active principles.


Medicinal plants Active principles Drug research Chromatographic techniques Espectrometric techniques Functional foods Stereoselective synthesis Biological assays Anticancer agents Phytotherapics

Editors and affiliations

  • Valdir Cechinel Filho
    • 1
  1. 1.University of Vale do Itajaí – UNIVALIItajaíBrazil

About the editors

Valdir Cechinel Filho is a Professor/researcher at the Postgraduate Program (M/D) in Pharmaceutical Sciences of the University of Vale do Itajaí (UNIVALI) in Santa Catarina, Brazil. He has experienced in the field of Organic Chemistry, focusing on the following topics: bioactive natural products, synthesis of molecules of biological interest, and investigation of the relationship between chemical structure and biological activity. Editor of six books, over twenty contributed chapters and over 300 papers and reviews, besides 12 patents. In 2017, he received the highest Commendation of Academic Merit of the Council of Rectors of Brazilian Universities (CRUB) for his contribution to the Brazilian Higher Education. In March 2018, he became President of the Foundation UNIVALI and Rector of UNIVALI, with a mandate to head the institution until 2022.

Bibliographic information

Industry Sectors
Chemical Manufacturing