© 2012

Clinical Research Informatics

  • Rachel L. Richesson
  • James E. Andrews

Part of the Health Informatics book series (HI)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Contexts of Clinical Research Informatics

    1. Front Matter
      Pages 1-1
    2. Rachel L. Richesson, James E. Andrews
      Pages 3-16
    3. Philip R. O. Payne
      Pages 27-48
    4. Antonella Bacchieri, Giovanni Della Cioppa
      Pages 49-79
    5. Chunhua Weng, Peter J. Embi
      Pages 81-93
    6. J. David Johnson, James E. Andrews
      Pages 95-112
    7. Stephane M. Meystre, Scott P. Narus, Joyce A. Mitchell
      Pages 113-131
  3. Data Management and Systems in Clinical Research

    1. Front Matter
      Pages 133-133
    2. Prakash M. Nadkarni, Luis N. Marenco, Cynthia A. Brandt
      Pages 135-154
    3. Ida Sim, Joyce C. Niland
      Pages 155-174
    4. Meredith Nahm
      Pages 175-201
    5. Robert O. Morgan, Kavita R. Sail
      Pages 203-220
    6. Elizabeth J. Horn, Sharon F. Terry
      Pages 221-231
    7. Rachel L. Richesson, Kendra Vehik
      Pages 233-252
  4. Knowledge Representation and Discovery

    1. Front Matter
      Pages 253-253
    2. Kin Wah Fung, Olivier Bodenreider
      Pages 255-275

About this book


Clinical research informatics (CRI) is the application of informatics principles and techniques to support the spectrum of activities and business processes that instantiate clinical research. Informatics, defined generally as the intersection of information and computer science with a health-related discipline, has a foundation drawn from many well-established, theory-based disciplines, including computer science, library and information science, cognitive science, psychology, and sociology. The newly articulated yet fundamental theorem of informatics states that information technology should be used to enable humans to function and perform better together than humans alone, and so informatics is a source for supportive technologies and tools that enhance – but not replace – unreservedly human processes.

Clinical Research Informatics contributes to the ongoing dialogues among researchers and practitioners in CRI as they continue to rise to the challenges of a dynamic and evolving clinical research environment. The development of CRI as a sub-discipline of informatics, and as an independent/maturing professional practice area in its own right, drives a growing pool of scientific literature based on original CRI research, and high-impact tools and systems will be developed. CRI leaders and stakeholder groups will continue to support and create communities of discourse that will address much needed practice standards in CRI, improved safety and efficiencies in clinical research, data standards in clinical research, policy issues, educational standards and instructional resources.

The Editors and contributors to this book are among the most active and engaged in the CRI domain and provide an excellent primer for deeper explorations into this emerging discipline. Certain themes are highlighted, including the changing role of the consumer, movement toward transparency, growing needs for global coordination and cooperation on many levels, and the merging together of clinical care delivery and research as part of a changing paradigm in global healthcare delivery – all in the context of rapid innovations in technology and explosions of data sources, types, and volume. This book is therefore of considerable interest to all students of biomedical informatics, from the newcomer to the professional informatician.


Clinical Research Global Healthcare Delivery Medical Informatics Theorem of Informatics

Editors and affiliations

  • Rachel L. Richesson
    • 1
  • James E. Andrews
    • 2
  1. 1.College of MedicineUniversity of South FloridaTampaUSA
  2. 2.College of MedicineUniversity of South FloridaTampaUSA

About the editors

Rachel Richesson, MS, PhD, MPH, FACMI, a noted informaticist, joined the Duke University School of Nuring in December 2011. Dr. Richesson earned her BS (Biology) at the University of Massachusetts in 1991, and holds graduate degrees in Community Health (MPH, 1995) and Health Informatics (MS, 2000 and PhD, 2003) from the University of Texas Health Sciences Center in Houston. Dr. Richesson spent 7 years as at the University of South Florida College of Medicine directing strategy for the identification and implementation of data standards for a variety of multi-national multi-site clinical research and epidemiological studies housed within the USF Department of Pediatrics, including the NIH Rare Diseases Clinical Research Network (RDCRN) and The Environmental Determinants of Diabetes in the Young (TEDDY) study.

Dr Andrews is the Director of the University of South Florida, School of Information, and an Associate Professor of Information Science. His research falls broadly within the interdisciplinary field of health informatics. He has specific interests in clinical research informatics, as well as health-related information behaviours, particularly in the context of cancer genetics. He works collaboratively with researchers from USF Health, within SI, and also across the US and internationally.

Bibliographic information

  • Book Title Clinical Research Informatics
  • Editors Rachel Richesson
    James E. Andrews
  • Series Title Health Informatics
  • DOI
  • Copyright Information Springer-Verlag London Limited 2012
  • Publisher Name Springer, London
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-84882-447-8
  • Softcover ISBN 978-1-4471-2660-7
  • eBook ISBN 978-1-84882-448-5
  • Series ISSN 1431-1917
  • Edition Number 1
  • Number of Pages IX, 419
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Health Informatics
    Health Administration
    Laboratory Medicine
  • Buy this book on publisher's site
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