© 2014

Therapeutic Applications of Ribozymes and Riboswitches

Methods and Protocols

  • Daniel Lafontaine
  • Audrey Dubé

Part of the Methods in Molecular Biology book series (MIMB, volume 1103)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Margaret J. Lange, Donald H. Burke
    Pages 11-29
  3. Robert J. Scarborough, Michel V. Lévesque, Jean-Pierre Perreault, Anne Gatignol
    Pages 31-43
  4. James R. Carter, Pruksa Nawtaisong, Velmurugan Balaraman, Malcolm J. Fraser Jr.
    Pages 57-66
  5. François D’Anjou, Frédéric Couture, Roxane Desjardins, Robert Day
    Pages 67-82
  6. Seong-Wook Lee, Jin-Sook Jeong
    Pages 83-95
  7. Preeti Bajaj, Christian Hammann
    Pages 97-111
  8. Amell El Korbi, Jonathan Ouellet, Mohammad Reza Naghdi, Jonathan Perreault
    Pages 113-126
  9. Francesco Colizzi, Anne-Marie Lamontagne, Daniel A. Lafontaine, Giovanni Bussi
    Pages 141-151
  10. Danielle Biscaro Pedrolli, Matthias Mack
    Pages 165-176
  11. Christina E. Lünse, Günter Mayer
    Pages 199-209
  12. Jason M. Thomas, Hua-Zhong Yu, Dipankar Sen
    Pages 267-276

About this book


In Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols, expert researchers in the field provide a complete overview of protocols used in the development of RNA molecule as drugs and drug target.  These include methods and protocols on recent and precise RNA molecule approaches or studies in the development of an RNA therapeutic tool. We are convinced that these methods will help researchers from various domains of life sciences, including clinicians, biochemists and virologists. Written in the highly successful Methods in Molecular Biology  series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.


Authoritative and practical, Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols seeks to aid scientists in the further development of new therapeutic applications implicating RNA molecules or directly targeting harmful RNA.


RNA molecule RNA therapeutic tool cleave RNA molecules diseases drug target drugs novel antimicrobial agents riboswitches ribozymes as silencing tools therapeutic applications viral genomes viroids

Editors and affiliations

  • Daniel Lafontaine
    • 1
  • Audrey Dubé
    • 2
  1. 1.Department of BiologyUniversité de SherbrookeCanada
  2. 2.Départment de biologieUniversité de SherbrookeSherbrookeCanada

Bibliographic information

  • Book Title Therapeutic Applications of Ribozymes and Riboswitches
  • Book Subtitle Methods and Protocols
  • Editors Daniel Lafontaine
    Audrey Dubé
  • Series Title Methods in Molecular Biology
  • Series Abbreviated Title Methods Molecular Biology
  • DOI
  • Copyright Information Springer Science+Business Media, New York 2014
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-1-62703-729-7
  • Softcover ISBN 978-1-4939-6296-9
  • eBook ISBN 978-1-62703-730-3
  • Series ISSN 1064-3745
  • Series E-ISSN 1940-6029
  • Edition Number 1
  • Number of Pages XI, 278
  • Number of Illustrations 34 b/w illustrations, 19 illustrations in colour
  • Topics Pharmacology/Toxicology
    Human Genetics
  • Buy this book on publisher's site
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