RNA Folding

Methods and Protocols

  • Christina Waldsich

Part of the Methods in Molecular Biology book series (MIMB, volume 1086)

Table of contents

  1. Front Matter
    Pages i-x
  2. Ivo L. Hofacker, Ronny Lorenz
    Pages 1-19
  3. Elisa Biondi, Donald H. Burke
    Pages 41-52
  4. Pablo Cordero, Wipapat Kladwang, Christopher C. VanLang, Rhiju Das
    Pages 53-77
  5. Nora Sachsenmaier, Stefan Handl, Franka Debeljak, Christina Waldsich
    Pages 79-94
  6. Matthew G. Seetin, Wipapat Kladwang, John P. Bida, Rhiju Das
    Pages 95-117
  7. Maria Costa, Dario Monachello
    Pages 119-142
  8. Michael Wildauer, Georgeta Zemora, Andreas Liebeg, Verena Heisig, Christina Waldsich
    Pages 159-176
  9. Sébastien H. Eschbach, Daniel A. Lafontaine
    Pages 255-264
  10. Harald Schwalbe, Boris Fürtig
    Pages 309-319
  11. Back Matter
    Pages 335-340

About this book


Focusing on in vitro and intracellular RNA structure formation, RNA Folding: Methods and Protocols provides a comprehensive collection of experimental protocols which are suitable to dissect RNA folding pathways and to characterize the structure of RNA folding intermediates at nucleotide or even atomic resolution. The presented techniques include powerful tools with a long tradition in RNA research as well as more advanced, novel methods, thus the methods span multiple disciplines, including molecular biology, biochemistry, biophysics, and computational biology.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Practical and authoritative, RNA Folding: Methods and Protocols serves as a vital reference for researchers attempting to gain insights into the secrets of this astounding macromolecule.


Folding pathway dissection In vivo studies Intracellular folding RNA folding intermediates RNA structure

Editors and affiliations

  • Christina Waldsich
    • 1
  1. 1.Dept. of Biochemistry & Cell BiologyUniversity of Vienna Max F. Perutz LaboratoriesViennaAustria

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2014
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-666-5
  • Online ISBN 978-1-62703-667-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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