Antiviral Methods and Protocols

  • Edwin Yunhao Gong

Part of the Methods in Molecular Biology book series (MIMB, volume 1030)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Human Immunodeficiency Virus Type 1 (HIV-1)

    1. Front Matter
      Pages 1-1
    2. Peggy Geluykens, Koen Van Acker, Johan Vingerhoets, Christel Van den Eynde, Marnix Van Loock, Géry Dams
      Pages 3-9
    3. Liesbet Smeulders, Lieve Bunkens, Inge Vereycken, Koen Van Acker, Pascale Holemans, Emmanuel Gustin et al.
      Pages 11-17
    4. Bertrand Van Schoubroeck, Marnix Van Loock, Tania Ivens, Pascale Dehertogh, Dirk Jochmans, Géry Dams
      Pages 19-24
    5. Marleen Clynhens, Alexandra Smets, Inge Vereycken, Marnix Van Loock, Reginald Clayton, Geert Meersseman et al.
      Pages 25-36
    6. Peter Van den Eede, Liesbeth Van Wesenbeeck, Yvan Verlinden, Maxim Feyaerts, Veerle Smits, Ann Verheyen et al.
      Pages 37-55
  3. Hepatitis Viruses

    1. Front Matter
      Pages 57-57
    2. Inge Vliegen, Leen Delang, Johan Neyts
      Pages 93-103
    3. Leen Vijgen, Jannick Verbeeck, Barbara Van Kerckhove, Jan Martin Berke, Diana Koletzki, Gregory Fanning et al.
      Pages 105-117
    4. Dawei Cai, Hui Nie, Ran Yan, Ju-Tao Guo, Timothy M. Block, Haitao Guo
      Pages 151-161
  4. Flaviviruses

    1. Front Matter
      Pages 183-183
    2. Edwin Yunhao Gong, Marleen Clynhens, Tania Ivens, Pedro Lory, Kenny Simmen, Guenter Kraus
      Pages 185-194
    3. Edwin Yunhao Gong, Alexandra Smets, Nick Verheyen, Marleen Clynhens, Emmanuel Gustin, Pedro Lory et al.
      Pages 195-203
    4. Wolfgang Fischl, Ralf Bartenschlager
      Pages 205-219
    5. Christoph Nitsche, Christian D. Klein
      Pages 221-236
    6. Edwin Yunhao Gong, Hannah Kenens, Tania Ivens, Koen Dockx, Katrien Vermeiren, Geneviève Vandercruyssen et al.
      Pages 237-247
    7. Siew Pheng Lim, Christophe Bodenreider, Pei-Yong Shi
      Pages 249-268
    8. Wouter Schul, Andy Yip, Pei-Yong Shi
      Pages 269-281
    9. Sofia L. Alcaraz-Estrada, Erin Donohue Reichert, Radhakrishnan Padmanabhan
      Pages 283-299
  5. Herpes Viruses

    1. Front Matter
      Pages 301-301
    2. Frances Valencia, Ronald L. Veselenak, Nigel Bourne
      Pages 315-326
    3. Christel Van den Eynde, Ellen Van Damme, Tania Ivens, Edwin Yunhao Gong
      Pages 327-334
  6. Respiratory Viruses

    1. Front Matter
      Pages 335-335
    2. Anna Lundin, Tomas Bergström, Edward Trybala
      Pages 345-363
    3. Lieselot Houspie, Hans Stevens, Maina Ngotho, Els Keyaerts, Gabriela Ispas, René Verloes et al.
      Pages 373-382
    4. Angela Luttick, Stephanie Hamilton, Simon P. Tucker
      Pages 383-406
  7. Alphaviruses

    1. Front Matter
      Pages 427-427
    2. Edwin Yunhao Gong, Jean-François Bonfanti, Tania Ivens, Marijke Van der Auwera, Barbara Van Kerckhove, Guenter Kraus
      Pages 429-438
    3. Ashley Dagley, Justin G. Julander
      Pages 439-448
  8. Back Matter
    Pages 449-452

About this book


Although antiviral drugs have been successfully developed for some viral diseases, there remains a clear, unmet medical need to develop novel antiviral agents for the control and management of many viruses that currently have no or limited treatment options as well as a need to overcome the limitations associated with the existing antiviral drugs, such as adverse effects and emergence of drug-resistant mutations. The second edition of Antiviral Methods and Protocols features:

  • All chapters are new and written by experts in the field, reflecting the major recent technical advances in antiviral research and discovery.
  • This edition focuses on many important human viruses, such as human immunodeficiency virus type 1 (HIV-1), hepatitis viruses (hepatitis B and C viruses), herpes viruses, human respiratory syncytial virus (RSV), and influenza virus, while also featuring some important emerging viruses, such as dengue virus, West Nile virus, and chikungunya virus. 
  • As a volume in the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Comprehensive and cutting-edge, Antiviral Methods and Protocols, Second Edition will serve as an excellent laboratory reference for pharmaceutical and academic biologists, medicinal chemists, and pharmacologists as well as for virologists in the field of antiviral research and drug discovery.


Antiviral drugs Dengue virus HIV-1 Hepatitis Human viruses Influenza Respiratory viruses

Editors and affiliations

  • Edwin Yunhao Gong
    • 1
  1. 1.Janssen Infectious Diseases-DiagnosticsJohnson & Johnson CorporationBeerseBelgium

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-483-8
  • Online ISBN 978-1-62703-484-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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