The Myc Gene

Methods and Protocols

  • Laura Soucek
  • Nicole M. Sodir

Part of the Methods in Molecular Biology book series (MIMB, volume 1012)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Nicole M. Sodir, Laura Soucek
    Pages 1-6
  3. Marie-Eve Beaulieu, François-Olivier McDuff, Mikaël Bédard, Martin Montagne, Pierre Lavigne
    Pages 7-20
  4. Markus Hartl, Klaus Bister
    Pages 21-49
  5. Romina Ponzielli, William B. Tu, Igor Jurisica, Linda Z. Penn
    Pages 51-64
  6. Dan Lu, Trevor D. Littlewood
    Pages 85-98
  7. Vedrana Tabor, Matteo Bocci, Lars-Gunnar Larsson
    Pages 99-116
  8. Bonnie L. Barrilleaux, Rebecca Cotterman, Paul S. Knoepfler
    Pages 117-133
  9. John T. Cunningham, Michael Pourdehnad, Craig R. Stumpf, Davide Ruggero
    Pages 201-212
  10. Anne Le, Chi V. Dang
    Pages 213-219
  11. David J. Huels, Patrizia Cammareri, Rachel A. Ridgway, Jan P. Medema, Owen J. Sansom
    Pages 237-248
  12. Catherine A. Burkhart, Michelle Haber, Murray D. Norris, Andrei V. Gudkov, Mikhail A. Nikiforov
    Pages 255-264
  13. Back Matter
    Pages 265-282

About this book


Myc controls multiple cellular functions, including cell proliferation, growth, differentiation and death, both directly and indirectly, through its modulation of downstream transcriptional programs. In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc mechanism of action in normal and cancer cells, in vitro and in vivo, in one succinct manual. Written in the highly successful Methods in Molecular Biology  series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.


Myc Myc mechanism cancer cancer therapy cellular functions in vitro and in vivo

Editors and affiliations

  • Laura Soucek
    • 1
  • Nicole M. Sodir
    • 2
  1. 1.Fundació Vall d'Hebron Institute of OncoBarcelonaSpain
  2. 2.Department of Biochemistry Sanger BuildingUniversity of CambridgeCambridgeUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-428-9
  • Online ISBN 978-1-62703-429-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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